College of Materials Science and Engineering, Nanjing Forestry University, Nanjing 210037, China.
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Org Lett. 2023 Mar 17;25(10):1638-1642. doi: 10.1021/acs.orglett.3c00140. Epub 2023 Mar 2.
Herein, we report a class of 1,4-bisvinylbenzene-bridged BODIPY dimers with fluorescence emission in the second near-infrared window (NIR-II, 1000-1700 nm). These dyes show excellent NIR-II fluorescence properties and can be easily functionalized to achieve good water-solubility or tumor-targeting ability. In vivo imaging results demonstrate that these dyes have high resolution and deep-penetration NIR-II imaging ability, which enable them to be used as promising NIR-II imaging agents.
在这里，我们报告了一类具有荧光发射的 1,4-双乙烯基苯桥联 BODIPY 二聚体，位于第二近红外窗口（NIR-II，1000-1700nm）。这些染料表现出优异的 NIR-II 荧光性能，并且可以很容易地进行功能化以实现良好的水溶性或肿瘤靶向能力。体内成像结果表明，这些染料具有高分辨率和深穿透 NIR-II 成像能力，使其成为有前途的 NIR-II 成像剂。
