Janetschek G, Schreckenberg F, Grimm W, Marberger M
Department of Urology, University of Mainz, Medical School, Federal Republic of Germany.
Urol Res. 1987;15(5):303-6. doi: 10.1007/BF00258201.
Experimental testicular torsion must be used for certain studies of clinical relevance, but most experimental models either do not provide hemodynamic alteration comparable to the clinical situation or cannot guarantee reproducibility. Using a rat model arterial perfusion and hemorrhagic infarction were correlated to the degree of both intra- and extravaginal testicular torsion. Arterial inflow was measured sequentially with radiolabelled microspheres, hemorrhagic infarction was judged by the increase of testicular weight. Maximal hemorrhagic infarction and reproducible values were found when the spermatic cord was twisted together with the tunica vaginalis for 360 degrees-540 degrees.
实验性睾丸扭转必须用于某些具有临床相关性的研究，但大多数实验模型要么无法提供与临床情况相当的血流动力学改变，要么无法保证可重复性。使用大鼠模型，将动脉灌注和出血性梗死与鞘内和鞘外睾丸扭转的程度相关联。用放射性标记的微球依次测量动脉流入量，通过睾丸重量的增加来判断出血性梗死。当精索与鞘膜一起扭转360度至540度时，发现了最大出血性梗死和可重复的值。
