Zhang Yatong, Wang Ai, Huang Bing, Liu Xiaowei, Englert Ulli, Lu Liping
Institute of Molecular Science, Key Laboratory of Chemical Biology and Molecular Engineering of the Education Ministry, Shanxi University, Taiyuan, Shanxi 030006, China.
Institute of Molecular Science, Key Laboratory of Chemical Biology and Molecular Engineering of the Education Ministry, Shanxi University, Taiyuan, Shanxi 030006, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jun 5;294:122470. doi: 10.1016/j.saa.2023.122470. Epub 2023 Feb 16.
A one-step solvothermal synthesis provides a functional crystalline one-dimensional Zn-coordination polymer (Zn-CP) with excellent stability in aqueous solution over a wide range of temperature and pH. Zn-CP is a rapid, highly sensitive and selective sensor for detecting tetracycline (TC). Quantitative TC detection is based on the ratio of fluorescence intensities I/I, with a limit of detection (LOD) of 5.51 nM in aqueous solution and 47.17 nM in human urine. The characteristics of colorimetric TC sensing by Zn-CP are highly favorable for application because the color of Zn-CP changes in the visible part of the spectrum from blue-purple to yellow-green upon addition of TC. Conversion of these colors into an RGB signal is simply achieved with an app for the smart phone and provides LODs of 8.04 nM and 0.13 μM TC in water and urine, respectively. Our suggested sensing mechanisms assume that the fluorescence intensity of Zn-CP@TC at 530 nm is enhanced by energy transfer of Zn-CP to TC, while the fluorescence of Zn-CP at 420 nm is quenched by photoinduced electron transfer (PET) from TC to the organic ligand in Zn-CP. These fluorescence properties make Zn-CP a convenient, low-cost, rapid and green detection device for monitoring TC under physiological conditions and in aqueous media.
一步溶剂热合成法制备了一种功能性晶体一维锌配位聚合物（Zn-CP），该聚合物在很宽的温度和pH范围内的水溶液中具有优异的稳定性。Zn-CP是一种用于检测四环素（TC）的快速、高灵敏度和高选择性传感器。TC的定量检测基于荧光强度比I/I₀，在水溶液中的检测限（LOD）为5.51 nM，在人尿中的检测限为47.17 nM。Zn-CP对TC进行比色传感的特性非常有利于应用，因为加入TC后，Zn-CP在光谱的可见光部分颜色从蓝紫色变为黄绿色。使用智能手机应用程序可轻松将这些颜色转换为RGB信号，在水和尿中检测TC的LOD分别为8.04 nM和0.13 μM。我们提出的传感机制假定，Zn-CP@TC在530 nm处的荧光强度通过Zn-CP向TC的能量转移而增强，而Zn-CP在420 nm处的荧光则通过从TC到Zn-CP中有机配体的光致电子转移（PET）而猝灭。这些荧光特性使Zn-CP成为一种方便、低成本、快速且绿色的检测装置，可用于在生理条件下和水性介质中监测TC。
