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mRNA 新冠疫苗接种后发生的前葡萄膜炎:病例报告。

Granulomatous anterior uveitis following mRNA-based COVID-19 vaccination: A case report.

机构信息

Department of Ophthalmology, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Indian J Ophthalmol. 2023 Mar;71(3):1033-1035. doi: 10.4103/ijo.IJO_1771_22.

Abstract

A 23-year-old patient presented with complaints of redness, pain, photophobia, and blurred vision in the right eye 15 days after she received the third dose of BNT162b2 vaccination. Ocular examination revealed 2+ cellular reactions in the anterior chamber and mutton fat keratic precipitate with no vitritis or retinal alterations. Active uveitis findings regressed with corticosteroid and cycloplegic eye drops. We present a case of unilateral granulomatous anterior uveitis following the BNT162b2 vaccination, with no etiologic factor in uveitis work-up and no previous history of uveitis before vaccination. This report demonstrates a potential causal association of coronavirus disease 2019 (COVID-19) vaccine with granulomatous anterior uveitis.

摘要

一位 23 岁患者在接种 BNT162b2 疫苗的第三剂后 15 天出现右眼发红、疼痛、畏光和视力模糊的症状。眼部检查显示前房有 2+细胞反应和棉絮状角膜后沉着物,无玻璃体炎症或视网膜改变。在皮质类固醇和睫状肌麻痹滴眼液的作用下,活动性葡萄膜炎消退。我们报告了一例 BNT162b2 疫苗接种后单侧肉芽肿性前葡萄膜炎病例,葡萄膜炎检查无病因,接种疫苗前也无葡萄膜炎病史。本报告表明 COVID-19 疫苗与肉芽肿性前葡萄膜炎之间存在潜在的因果关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3665/10229926/aefde4f497fc/IJO-71-1033-g001.jpg

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