Garry P J, Hunt W C, Bandrofchak J L, VanderJagt D, Goodwin J S
Department of Pathology, University of New Mexico School of Medicine, Albuquerque 87131.
Am J Clin Nutr. 1987 Dec;46(6):989-94. doi: 10.1093/ajcn/46.6.989.
We examined intakes of vitamin A (diet plus supplement) and plasma retinol levels in a select group of elderly men (n = 90) and women (n = 110) on three separate occasions over a 4-y period. Median dietary levels remained at approximately 1400 retinol equivalents (RE) in men and 1250 RE in women. There were no time trends or gender differences noted in plasma retinol concentrations. Approximately 44% of the elderly men and women consumed an average of 2000 RE of a vitamin A supplement daily. Those taking supplement had a greater mean plasma retinol concentration than those not taking a supplement. This effect was greater in men than in women. A review of previous studies revealed that plasma retinol increases from a mean of approximately 35 micrograms/dL (1.22 mumol/L) at preschool age to a plateau of approximately 60 micrograms/dL (2.09 mumol/L) by age 40 y in men and 60 y in women.
我们在4年时间内分三次对一组特定的老年男性(n = 90)和女性(n = 110)的维生素A摄入量(饮食加补充剂)和血浆视黄醇水平进行了检测。男性的膳食水平中位数保持在约1400视黄醇当量(RE),女性为1250 RE。血浆视黄醇浓度未发现时间趋势或性别差异。约44%的老年男性和女性每天平均摄入2000 RE的维生素A补充剂。服用补充剂者的平均血浆视黄醇浓度高于未服用补充剂者。这种效应在男性中比在女性中更明显。对先前研究的回顾显示,血浆视黄醇从学龄前儿童时期的平均约35微克/分升(1.22微摩尔/升)增加到40岁男性和60岁女性时的约60微克/分升(2.09微摩尔/升)的稳定水平。