Lilienfeld D E, Gunderson P D, Sprafka J M, Vargas C
Division of Disease Prevention and Health Promotion, Minnesota Department of Health, Minneapolis.
Arteriosclerosis. 1987 Nov-Dec;7(6):637-43. doi: 10.1161/01.atv.7.6.637.
The trends in mortality from aortic aneurysms in the United States from 1951 through 1981 were studied. Annual age-specific and age-adjusted mortality for aortic aneurysms were calculated for white males, white females, nonwhite males, and nonwhite females. For all four groups, a constant increase in age-adjusted mortality was noted for the period 1951 to 1968 (an average annual increase of 17% for white males, 12% for white females, 14% for nonwhite males, and 15% for nonwhite females), plateauing in 1968, with a slight decline noted after 1968. The increase corresponded to an increase in the total number of U.S. aortic aneurysm deaths from about 2500 to approximately 14,000. The decline was most notable for dissecting aneurysms. Analysis of the age-specific rates by birth cohort suggests that mortality is increasing with each subsequent cohort. Analysis of specific aneurysm types (dissecting, thoracic, abdominal, and not otherwise specified) suggests that abdominal ones are most common. These data are reviewed in the context of existing knowledge of aortic aneurysms. Further studies to validate these findings and to develop hypotheses for the etiology of aortic aneurysms are needed.
研究了1951年至1981年美国主动脉瘤死亡率的趋势。计算了白人男性、白人女性、非白人男性和非白人女性的主动脉瘤年度年龄别死亡率和年龄调整死亡率。对于所有这四组人群，在1951年至1968年期间年龄调整死亡率持续上升（白人男性平均每年上升17%，白人女性为12%，非白人男性为14%，非白人女性为15%），1968年趋于平稳，1968年后略有下降。这种上升与美国主动脉瘤死亡总数从约2500例增加到约14000例相对应。下降在夹层动脉瘤中最为明显。按出生队列分析年龄别死亡率表明，死亡率随随后的每个队列而增加。对特定动脉瘤类型（夹层、胸段、腹段和未另行指定的）的分析表明，腹段动脉瘤最为常见。结合现有的主动脉瘤知识对这些数据进行了综述。需要进一步研究以验证这些发现并为主动脉瘤的病因提出假设。
