Department of Biology, College of Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
PLoS One. 2023 Mar 9;18(3):e0282443. doi: 10.1371/journal.pone.0282443. eCollection 2023.
Saussurea costus is from medicinal plants and have therapeutic properties that were recorded in a variety of medical functions. The usage of biomaterials in the synthesis of nanoparticles is an essential strategy in green nanotechnology. Iron oxide nanoparticles (IONPs) were composed in the stage of (2:1, FeCl2: FeCl3) solution by using the aqueous extract of Saussurea costus peel in an eco-friendly method to evaluate their antimicrobial property. The properties of the obtained IONPs were evaluated using a scanning (SEM) and transmission (TEM) electron microscope. The mean size of IONPs discovered by Zetasizer varies between 100 and 300 nm, with a mean particle size of 295 nm. The morphology of IONPs (γ-Fe2O3) was determined to be nearly spherical and prismatic-curved. Moreover, the antimicrobial property of IONPs was assessed with nine pathogenic microbes, revealing that the nanoparticles have antimicrobial activities with Pseudomonas aeruginosa, Escherichia coli, Shigella sp., Staphylococcus sp. and Aspergillus niger, with possible applications in the therapeutic and biomedical fields.
雪莲花是一种药用植物，具有多种医疗功效，在各种医学功能中都有记载。生物材料在纳米粒子合成中的应用是绿色纳米技术的重要策略。在环保的方法中，通过使用雪莲花皮的水提物，在（2：1，FeCl2：FeCl3）溶液的阶段合成了氧化铁纳米粒子（IONPs），以评估其抗菌性能。使用扫描电子显微镜（SEM）和透射电子显微镜（TEM）评估所获得的 IONPs 的性质。Zetasizer 发现的 IONPs 的平均尺寸在 100 到 300nm 之间，平均粒径为 295nm。IONPs（γ-Fe2O3）的形态被确定为近球形和棱柱形弯曲。此外，还评估了 IONPs 的抗菌性能，结果表明，纳米粒子对铜绿假单胞菌、大肠杆菌、志贺氏菌、葡萄球菌和黑曲霉等 9 种致病微生物具有抗菌活性，可能在治疗和生物医学领域得到应用。
