Patel Vashistha M, Patel Shreya V
Internal Medicine, Brookwood Baptist Health, Birmingham, USA.
Cureus. 2023 Feb 5;15(2):e34653. doi: 10.7759/cureus.34653. eCollection 2023 Feb.
The significant increase in monkeypox cases that was reported at the beginning of 2022 was notable. The resurgence of viral zoonosis is especially concerning, given the current and recent COVID-19 epidemic. There are worries that a new pandemic may be beginning due to the virus that causes monkeypox spreading so quickly. This article aimed to provide an overview of the epidemiology, pathogenesis, and clinical symptoms of monkeypox. It has been known that monkeypox was primarily prevalent in Central and West Africa, but in recent years, cases of monkeypox infections have been reported around the world. The transmission of the infection to humans has been connected to exposure to a diseased animal or person's excretions and secretions. Various studies indicate that monkeypox clinically manifests as fever, fatigue, and a rash of smallpox-like lesions and can cause various complications, including pneumonia, encephalitis, and sepsis, which, when not properly managed, can lead to death. Those living in remote and forested areas, taking care of individuals infected with monkeypox, and trading and taking care of exotic animals are some of the risk factors for monkeypox. Men having sex with men are also at higher risk of contracting monkeypox. When dealing with individuals who have high-risk factors and come with new-onset progressive rashes, it is necessary for clinicians to highly suspect monkeypox. This review will serve as reference material and a supplement to the existing literature that will assist in the proper management and prevention of monkeypox.
2022年初报告的猴痘病例显著增加,这一情况值得关注。鉴于当前及近期的新冠疫情,这种病毒性人畜共患病的再度出现尤其令人担忧。人们担心,由于导致猴痘的病毒传播速度如此之快,一场新的大流行可能正在开始。本文旨在概述猴痘的流行病学、发病机制和临床症状。已知猴痘主要在中非和西非流行,但近年来,世界各地都报告了猴痘感染病例。感染传播给人类与接触患病动物或人的排泄物和分泌物有关。各种研究表明,猴痘在临床上表现为发热、疲劳以及出现类似天花的皮疹,并且可能引发各种并发症,包括肺炎、脑炎和败血症,若处理不当,可能导致死亡。生活在偏远和森林地区、照顾感染猴痘的个人以及交易和照顾外来动物等都是感染猴痘的一些风险因素。男男性行为者感染猴痘的风险也更高。当面对有高危因素且出现新发进行性皮疹的个体时,临床医生有必要高度怀疑猴痘。本综述将作为参考资料和对现有文献的补充,有助于对猴痘进行妥善管理和预防。