同一枚硬币的两面：新冠病毒刺突蛋白的N端结构域和受体结合结构域
Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike.
作者信息
Ciccozzi Massimo, Pascarella Stefano
机构信息
Medical Statistic & Molecular Epidemiology Unit, University of Biomedical Campus, Rome, Italy.
Department of Biochemical Sciences 'A Rossi Fanelli', Sapienza Università di Roma, Rome, 00185, Italy.
出版信息
Future Virol. 2023 Feb. doi: 10.2217/fvl-2022-0181. Epub 2023 Mar 6.
Abstract
The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.
摘要
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突蛋白受体结合域与N端结构域以一种复杂的机制相互作用。突变会调节刺突蛋白与宿主分子之间的相互作用。这篇社论评论了SARS-CoV-2刺突蛋白相互作用的复杂性。
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