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一例罕见的咽后脂肪肉瘤:罕见诊断的罕见部位。

A rare case of retropharyngeal liposarcoma: a rare location of a rare diagnosis.

作者信息

Arshad Wajiha, Maqbool Shahzaib, Kiany Javeria A, Raza Ali, Farooq Umer, Ali Qasim, Lee Ka Y

机构信息

Department of Surgical Unit II, Holy Family Hospital, Rawalpindi, Pakistan.

出版信息

J Surg Case Rep. 2023 Mar 7;2023(3):rjad106. doi: 10.1093/jscr/rjad106. eCollection 2023 Mar.

DOI:10.1093/jscr/rjad106
PMID:36896154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9991594/
Abstract

We report a case of retropharyngeal liposarcoma in a 53-year-old female, who had complaints of neck swelling accompanied with dysphagia, orthopnea and dysphonia. Clinical examination revealed huge multinodular swelling in front of neck with bilateral extension, more prominent on left side and moving with deglutition. The diagnosis of retropharyngeal liposarcoma was established following CT scan, MRI and incisional biopsy. Surgical excision of mass along with near total thyroidectomy was performed. Postoperative hospital stay was uneventful. She remained well in follow-up period of 1 year as well. In conclusion, retropharyngeal liposarcoma is a rare tumor. A review of the literature explores the reasons behind the late presentation as well as the difficulties in diagnosis and treatment of this rare tumor.

摘要

我们报告一例53岁女性的咽后脂肪肉瘤病例,该患者主诉颈部肿胀并伴有吞咽困难、端坐呼吸和声音嘶哑。临床检查发现颈部前方巨大的多结节性肿胀,向双侧延伸,左侧更明显,且随吞咽动作移动。经CT扫描、MRI及切开活检后确诊为咽后脂肪肉瘤。遂行肿物手术切除及近全甲状腺切除术。术后住院期间情况平稳。在1年的随访期内她也恢复良好。总之,咽后脂肪肉瘤是一种罕见肿瘤。文献综述探讨了该罕见肿瘤出现延迟表现的原因以及诊断和治疗方面的困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/74d1c768d99e/rjad106f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/2d6bc7c11bb6/rjad106f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/a22da35fee9a/rjad106f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/0018317f814c/rjad106f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/74d1c768d99e/rjad106f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/2d6bc7c11bb6/rjad106f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/a22da35fee9a/rjad106f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/0018317f814c/rjad106f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1621/9991594/74d1c768d99e/rjad106f4.jpg

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2
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Transl Cancer Res. 2021 Jul;10(7):3600-3604. doi: 10.21037/tcr-21-143.
3
Value of intraoperative pathological diagnosis in decision-making regarding resection of well-differentiated retropharyngeal liposarcoma: A case report.
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4
Biology and Management of Dedifferentiated Liposarcoma: State of the Art and Perspectives.去分化脂肪肉瘤的生物学特性与管理:现状与展望
J Clin Med. 2021 Jul 22;10(15):3230. doi: 10.3390/jcm10153230.
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Soft-tissue sarcoma in adults: An update on the current state of histiotype-specific management in an era of personalized medicine.成人软组织肉瘤:在个体化医学时代,组织亚型特异性管理的最新进展。
CA Cancer J Clin. 2020 May;70(3):200-229. doi: 10.3322/caac.21605. Epub 2020 Apr 10.
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Liposarcoma: Advances in Cellular and Molecular Genetics Alterations and Corresponding Clinical Treatment.脂肪肉瘤:细胞与分子遗传学改变及相应临床治疗的进展
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