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美国婴儿和幼儿致命中毒的特征。

Characteristics of Fatal Poisonings Among Infants and Young Children in the United States.

机构信息

Divisions of Emergency Medicine.

Centers for Injury Research and Prevention.

出版信息

Pediatrics. 2023 Apr 1;151(4). doi: 10.1542/peds.2022-059016.

Abstract

BACKGROUND AND OBJECTIVES

Fatal poisoning is a preventable cause of death among young children. Understanding factors surrounding these deaths will inform future prevention efforts. Our objective was to describe the characteristics of fatal pediatric poisonings using child death review data.

METHODS

We acquired data from 40 states participating in the National Fatality Review-Case Reporting System on deaths attributed to poisonings among children aged ≤5 years from 2005 to 2018. We analyzed select demographic, supervisor, death investigation, and substance-related variables using descriptive statistics.

RESULTS

During the study period, 731 poisoning-related fatalities were reported by child death reviews to the National Fatality Review-Case Reporting System. Over two-fifths (42.1%, 308 of 731) occurred among infants aged <1 year, and most fatalities (65.1%, 444 of 682) occurred in the child's home. One-sixth of children (97 of 581) had an open child protective services case at time of death. Nearly one-third (32.2%, 203 of 631) of children were supervised by an individual other than the biological parent. Opioids (47.3%, 346 of 731) were the most common substance contributing to death, followed by over-the-counter pain, cold, and allergy medications (14.8%, 108 of 731). Opioids accounted for 24.1% (7 of 29) of the substances contributing to deaths in 2005 compared with 52.2% (24 of 46) in 2018.

CONCLUSIONS

Opioids were the most common substances contributing to fatal poisonings among young children. Over-the-counter medications continue to account for pediatric fatalities even after regulatory changes. These data highlight the importance of tailored prevention measures to further reduce fatal child poisonings.

摘要

背景和目的

致命性中毒是导致幼儿死亡的可预防原因。了解这些死亡事件背后的因素将为未来的预防工作提供信息。我们的目的是使用儿童死亡回顾数据描述致命性儿科中毒的特征。

方法

我们从参与国家致命性审查-病例报告系统的 40 个州获取了数据,该系统报告了 2005 年至 2018 年 5 岁以下儿童因中毒导致的死亡。我们使用描述性统计方法分析了选择的人口统计学、监督者、死亡调查和物质相关变量。

结果

在研究期间,国家致命性审查-病例报告系统收到了儿童死亡回顾报告的 731 例与中毒相关的致命事件。超过五分之二(42.1%,308/731)发生在年龄<1 岁的婴儿中,大多数致命事件(65.1%,444/682)发生在儿童的家中。六分之一的儿童(97/581)在死亡时存在开放的儿童保护服务案件。将近三分之一(32.2%,203/631)的儿童由非亲生父母的人监督。阿片类药物(47.3%,346/731)是导致死亡的最常见物质,其次是非处方止痛、感冒和过敏药物(14.8%,108/731)。与 2005 年的 24.1%(29 例中的 7 例)相比,阿片类药物在 2018 年导致死亡的物质中占 52.2%(46 例中的 24 例)。

结论

阿片类药物是导致幼儿致命性中毒的最常见物质。即使在监管变化之后,非处方药物仍会导致儿科死亡。这些数据强调了制定有针对性的预防措施以进一步减少儿童致命性中毒的重要性。

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