Stepanova Marina V, Sotnikova Larisa F, Zaitsev Sergei Yu
Department of Bioecology and Biological Safety, Federal State Budgetary Educational Institution of Higher Education "Russian Biotechnological University (ROSBIOTECH)", Volokolamsk Highway, 11, 125080 Moscow, Russia.
Research Laboratory of Ophthalmology, Oncology and Biochemistry of Animals, ROSBIOTECH, 125080 Moscow, Russia.
Animals (Basel). 2023 Feb 26;13(5):852. doi: 10.3390/ani13050852.
Many of the micro- and macro-elements (MMEs) required by the body are found in environmental objects in concentrations different from their original concentration that can lead to dangerous animal diseases ("microelementoses"). The aim was to study the features of MME (accumulating in wild and exotic animals) in connection with particular diseases. The work using 67 mammal species from four Russian zoological institutions was completed in 2022. Studies of 820 cleaned and defatted samples (hair, fur, etc.) after "wet-acid-ashing" on an electric stove and in a muffle furnace were performed using a Kvant-2A atomic absorption spectrometer. The content of zinc, copper, iron, cadmium, lead, and arsenic was assessed. The level of MME accumulation in the animal body contributes not only to the MME status and the development of various concomitant diseases, but the condition itself can occur by intake of a number of micronutrients and/or drugs. Particular correlations between the accumulation of Zn and skin, oncological diseases, Cu-musculoskeletal, cardiovascular diseases, Fe-oncological diseases, Pb-metabolic, nervous, oncological diseases, and Cd-cardiovascular diseases were established. Therefore, monitoring of the MME status of the organism must be carried out regularly (optimally once every 6 months).
人体所需的许多微量元素和宏量元素在环境物体中的浓度与它们的原始浓度不同，这可能导致危险的动物疾病（“微量元素病”）。目的是研究与特定疾病相关的微量元素和宏量元素（在野生动物和外来动物体内积累）的特征。这项使用来自俄罗斯四个动物园机构的67种哺乳动物的工作于2022年完成。使用Kvant - 2A原子吸收光谱仪对在电炉和马弗炉中进行“湿酸灰化”后的820个清洁和脱脂样本（毛发、皮毛等）进行了研究。评估了锌、铜、铁、镉, 铅和砷的含量。动物体内微量元素和宏量元素的积累水平不仅有助于微量元素和宏量元素的状态以及各种伴随疾病的发展，而且这种状况本身可能通过摄入多种微量营养素和/或药物而发生。锌的积累与皮肤、肿瘤疾病，铜与肌肉骨骼、心血管疾病，铁与肿瘤疾病，铅与代谢、神经、肿瘤疾病，镉与心血管疾病之间建立了特定的相关性。因此，必须定期（最好每6个月一次）对生物体的微量元素和宏量元素状态进行监测。
