Department of Ophthalmology, Ain Shams University Hospitals, Ramses St., Abbasiya, Cairo, 11517, Egypt.
Int Ophthalmol. 2023 Aug;43(8):2983-2987. doi: 10.1007/s10792-023-02681-7. Epub 2023 Mar 11.
To examine the long-term effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the corneal endothelium.
This was a comparative, cross-sectional study that included subjects who had recovered from SARS-CoV-2 infection for at least 6 months (group 1) and a group of age- and sex-matched controls with no prior symptomatology or documentation of SARS-CoV-2 infection (group 2). After full ophthalmological evaluation, specular microscopy was used to examine the endothelial cell parameters, including endothelial cell density, coefficient of variation, hexagonality, average area, and central corneal thickness.
Sixty-four and 53 right eyes were included in groups 1 and 2, respectively. No statistically significant differences were detected in any of the examined specular parameters between the two groups.
SARS-CoV-2 infection may have no delayed sequel on the corneal endothelium. Future prospective studies with repeated examinations in the same subjects would be useful.
研究严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染对角膜内皮的长期影响。
这是一项比较性、横断面研究，纳入至少 6 个月前从 SARS-CoV-2 感染中康复的受试者（第 1 组）和一组年龄和性别匹配、无先前症状或 SARS-CoV-2 感染记录的对照组（第 2 组）。在全面的眼科评估后，使用共焦显微镜检查内皮细胞参数，包括内皮细胞密度、变异系数、六边形、平均面积和中央角膜厚度。
第 1 组和第 2 组分别纳入 64 只和 53 只右眼。两组间任何检查的镜面参数均无统计学差异。
SARS-CoV-2 感染可能不会对角膜内皮产生延迟性后遗症。未来对同一受试者进行重复检查的前瞻性研究将很有帮助。
