不同营养干预措施对肌少症的影响：系统评价和网络荟萃分析方案。
Impact of different nutritional approaches on sarcopenia: a protocol for systematic review and network meta-analysis.
机构信息
Department of Acupuncture & Moxibustion, Kyung Hee University Hospital, Gangdong, 892, Dongnam-ro, Gangdong-gu, Seoul, 05278, Republic of Korea.
Department of Orthopaedic Surgery, Kyung Hee University Hospital, Gangdong, 892, Dongnam-ro, Gangdong-gu, Seoul, 05278, Republic of Korea.
出版信息
Syst Rev. 2023 Mar 13;12(1):37. doi: 10.1186/s13643-023-02215-3.
Although it is known that proper nutrition is effective in managing sarcopenia, the most powerful nutrients have not yet been determined. This study is designed to investigate the effects of various nutritional approaches on muscle mass, muscle strength, and sarcopenia prevention in systematic reviews. In study design, network and pairwise meta-analyses of randomized clinical trials were considered. Clinical studies regarding the nutritional effects associated with the physiological activity of skeletal muscle and management of sarcopenia will be covered. The main outcomes will cover the following five elements: anti-fatigue impact with skeletal muscle, muscle atrophy prevention, differentiation level with skeletal muscular cell, anti-inflammatory effect, and muscle injury prevention. Authors will conduct the study selection, extracting data process, and methodological quality investigation.Systematic review registrationOSF registry (ethical approval number: https://osf.io/ye4q7 ).
尽管人们知道适当的营养对于肌少症的管理是有效的，但最有效的营养素尚未确定。本研究旨在通过系统评价调查各种营养方法对肌肉质量、肌肉力量和肌少症预防的影响。在研究设计中，考虑了网络和成对的随机临床试验的荟萃分析。涵盖了与骨骼肌肉生理活动相关的营养作用以及肌少症管理的临床研究。主要结果将涵盖以下五个要素：抗骨骼肌肉疲劳影响、预防肌肉萎缩、骨骼肌细胞分化水平、抗炎作用和预防肌肉损伤。作者将进行研究选择、提取数据过程和方法学质量调查。系统评价注册 OSF 注册表（伦理批准号：https://osf.io/ye4q7 ）。
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