Ciccarese Giulia, Di Biagio Antonio, Drago Francesco, Mastrolonardo Mario, Pipoli Antonietta, Lo Caputo Sergio, Serviddio Gaetano, Santantonio Teresa, Parodi Aurora
Unit of Dermatology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Infectious Diseases Unit, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy.
Infez Med. 2023 Mar 1;31(1):113-115. doi: 10.53854/liim-3101-16. eCollection 2022.
In our case series of monkeypox (MPX) virus infected patients, one had a single genital ulcer as the only cutaneous manifestation of the infection. Physical examination revealed a single, rounded ulcer of the shaft penis characterized by pinkish raised, infiltrated borders and a crusty yellowish bottom associated with bilateral inguinal lymphadenopathies. Serology for infection and a complete screening for sexually transmitted infections (STIs) resulted negative except for the detection of at the cultural examination and MPX DNA at the ulcer bottom. The patient's general conditions were good therefore he remained isolated at home for 3 weeks after the diagnosis. At one month follow up, he presented only a depressed pinkish skin scars on the site of the previous ulcer. The clinical presentation of this patient could easily be misdiagnosed with other sexually transmitted infections (STIs), especially with primary syphilis. MPX infection should be considered in the differential diagnosis of STIs, also in patients with weak and localized manifestations.
在我们的猴痘（MPX）病毒感染患者病例系列中，有一名患者仅有单个生殖器溃疡作为感染的唯一皮肤表现。体格检查发现阴茎体有一个单一的圆形溃疡，其特征为边界呈粉红色隆起、浸润，底部为结痂的淡黄色，伴有双侧腹股沟淋巴结病。感染血清学检查以及性传播感染（STIs）的全面筛查结果均为阴性，仅在培养检查中检测到[此处原文缺失相关检测物]，在溃疡底部检测到猴痘病毒DNA。患者一般状况良好，因此诊断后在家隔离3周。在1个月的随访中，他仅在前溃疡部位出现了一个凹陷的粉红色皮肤瘢痕。该患者的临床表现很容易被误诊为其他性传播感染（STIs），尤其是一期梅毒。在性传播感染的鉴别诊断中，即使是表现轻微和局限的患者，也应考虑猴痘感染。
