Audunsdottir Kristin, Quintana Daniel S
Department of Psychology, University of Oslo, Oslo, Norway.
Norwegian Centre for Mental Disorders Research (NORMENT), University of Oslo, Oslo, Norway.
Aging Brain. 2022 Jan 25;2:100028. doi: 10.1016/j.nbas.2021.100028. eCollection 2022.
Older adults have been neglected in biobehavioral oxytocin research. Emerging research indicates that oxytocin signaling activity fluctuates over the lifespan, which suggests that results from studies investigating youth and young adults cannot be easily generalized to older adults. The recruitment of a wider age range of research participants using a variety of research tools is required to uncover the role of the oxytocin signaling system over the lifespan and may reveal novel treatment target candidates in older adults, beyond social cognition and behavior.
在生物行为催产素研究中,老年人一直被忽视。新出现的研究表明,催产素信号传导活动在整个生命周期中会发生波动,这意味着针对青年人和年轻人的研究结果不能轻易推广到老年人身上。需要使用各种研究工具招募更广泛年龄范围的研究参与者,以揭示催产素信号系统在整个生命周期中的作用,并且可能会揭示老年人除社会认知和行为之外的新的治疗靶点候选物。