Mishra Navya, Bhagat Manisha, Haque Ekramul
Anaesthesiology, Rajendra Institute of Medical Sciences, Ranchi, IND.
Cureus. 2023 Feb 6;15(2):e34666. doi: 10.7759/cureus.34666. eCollection 2023 Feb.
Postoperative pain is an inevitable acute pain for which a multimodal analgesic approach is required. The aim of this study was to quantify and compare the efficacy of transverse abdominis plane (TAP) block as a postoperative analgesic for patients undergoing laparoscopic hysterectomies versus intravenous opioid analgesics.
Sixty female patients were enrolled and randomized into two groups following a computer-generated sequence of numbers. In group T (n=30) patients received an ultrasound-guided bilateral TAP block with 20 of 0.375% levobupivacaine on each side immediately after surgery. Patients in group O (opioid group, n = 30) received intravenous (i.v.) tramadol (100mg) immediately after surgery. Rescue analgesic (inj. tramadol 50mg) i.v. bolus given in both groups if visual analog scale (VAS) >4. In the postanesthesia care unit (PACU), the vital signs, episodes of nausea, vomiting, and VAS score of each patient were recorded every two hours for the first 24 hours.
Total consumption of rescue analgesic (inj. tramadol 50 mg i.v.) during the first 24 hours was significantly higher in group O (186.47+37.48mg) than in group T (107.28+26.34mg). No significant difference was observed in intraoperative vital parameters (HR, NIBP, SPO). The VAS scores were significantly low in group T. Incidence of postoperative nausea and vomiting (PONV) was significantly higher in group O (13 out of 28 patients) than in group T (five out of 28 patients) with P value =0.043.
Our study indicated bilateral ultrasound-guided TAP block is a good alternative to opioids for postoperative analgesia.
术后疼痛是一种不可避免的急性疼痛,需要采用多模式镇痛方法。本研究的目的是量化并比较腹横肌平面(TAP)阻滞作为腹腔镜子宫切除术患者术后镇痛方法与静脉注射阿片类镇痛药的疗效。
纳入60例女性患者,按照计算机生成的数字序列随机分为两组。T组(n = 30)患者在术后立即接受超声引导下双侧TAP阻滞,每侧注射20ml 0.375%左旋布比卡因。O组(阿片类药物组,n = 30)患者在术后立即静脉注射曲马多(100mg)。若视觉模拟评分(VAS)>4,则两组均静脉推注急救镇痛药(曲马多注射液50mg)。在麻醉后监护病房(PACU),术后24小时内每两小时记录每位患者的生命体征、恶心、呕吐发作情况及VAS评分。
O组(186.47 + 37.48mg)术后24小时内急救镇痛药(曲马多注射液50mg静脉注射)的总消耗量显著高于T组(107.28 + 26.34mg)。术中生命参数(心率、无创血压、脉搏血氧饱和度)无显著差异。T组的VAS评分显著较低。O组术后恶心呕吐(PONV)的发生率(28例患者中有13例)显著高于T组(28例患者中有5例),P值 = 0.043。
我们的研究表明,双侧超声引导下的TAP阻滞是术后镇痛替代阿片类药物的良好选择。