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腹腔镜胆囊切除术中腹腔镜腹横肌平面(TAP)阻滞的疗效和成本效益:与非TAP组的比较

Efficacy and Cost-Effectiveness of Laparoscopic Transversus Abdominis Plane (TAP) Block in Laparoscopic Cholecystectomy: A Comparison With the Non-TAP Group.

作者信息

Nair Pallavi, Behera Chinmaya R, Patra Rajat K, Shekar Nithya, Rao Lakshmi S, Pujari Pransingh, Panda Bandita, Mishra Amaresh

机构信息

Department of Surgery, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.

Department of Research and Development, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.

出版信息

Cureus. 2022 Nov 30;14(11):e32038. doi: 10.7759/cureus.32038. eCollection 2022 Nov.

Abstract

BACKGROUND

Postoperative pain caused by laparoscopic cholecystectomy can be controlled by different methods. The study aimed to observe the efficacy of laparoscopic transversus abdominis plane (TAP) block in laparoscopic cholecystectomy and to analyze the cost-effectiveness of the procedure in comparison to the non-TAP method.

METHODS

In this double-blinded randomized clinical trial, the subjects who had come for cholecystectomy were randomly divided into two groups (n = 43 in each group). Group A received laparoscopy-guided subcostal TAP block bilaterally (0.25% bupivacaine, 20 ml each) along with parenteral analgesics (100 mg tramadol injection in 100 ml normal saline IV) SOS as rescue analgesia, and group B received parenteral analgesics (injection paracetamol 1 gm IV) eight hourly and injection tramadol 100 mg in 100 ml normal saline IV SOS as rescue analgesia.

RESULT

A bulge was visualized by the surgeon through a laparoscope as a signature view for confirming the placement of local anesthetic in TAP. Based on the Visual Analog Scale (VAS) for assessment of postoperative pain and the Numeric Rating Scale (NRS) for assessment of pain at 30 minutes, four hours, eight hours, 12 hours, and 24 hours postoperatively, patients of both groups were assessed. According to the VAS, the pain assessment was better in the TAP block group at 30 minutes post-surgery than in the non-TAP group. As a primary outcome, 37% of TAP block group cases were recovered without any rescue analgesia. VAS score revealed a significant difference in postoperative nausea and vomiting (PONV) among the TAP block and non-TAP groups. PONV at four hours, eight hours, and 12 hours showed significantly lesser incidences in the TAP group as compared to the non-TAP group (p-value: 0.015, 0.028, and 0.055, respectively).

CONCLUSION

The cost-effectiveness of the TAP block method is 20 times lesser than the non-TAP method. Thus, a laparoscopic-guided TAP block could offer better postoperative analgesia at a low cost with a similar advantage to a USG-guided TAP block.

摘要

背景

腹腔镜胆囊切除术引起的术后疼痛可通过不同方法控制。本研究旨在观察腹腔镜腹横肌平面(TAP)阻滞在腹腔镜胆囊切除术中的疗效,并与非TAP方法比较分析该手术的成本效益。

方法

在这项双盲随机临床试验中,前来接受胆囊切除术的受试者被随机分为两组(每组n = 43)。A组接受腹腔镜引导下双侧肋下TAP阻滞(0.25%布比卡因,每侧20 ml),并按需使用胃肠外镇痛药(100 mg曲马多注射液加入100 ml生理盐水中静脉注射)作为补救镇痛;B组每8小时接受一次胃肠外镇痛药(1 g对乙酰氨基酚注射液静脉注射),并按需使用100 mg曲马多注射液加入100 ml生理盐水中静脉注射作为补救镇痛。

结果

外科医生通过腹腔镜观察到一个隆起,作为确认局部麻醉药在TAP中位置的标志性视图。根据用于评估术后疼痛的视觉模拟量表(VAS)和用于评估术后30分钟、4小时、8小时、12小时和24小时疼痛的数字评定量表(NRS),对两组患者进行评估。根据VAS,TAP阻滞组术后30分钟的疼痛评估优于非TAP组。作为主要结果,37%的TAP阻滞组病例在未使用任何补救镇痛的情况下康复。VAS评分显示TAP阻滞组和非TAP组术后恶心呕吐(PONV)存在显著差异。与非TAP组相比,TAP组在4小时、8小时和12小时的PONV发生率显著较低(p值分别为0.015、0.028和0.055)。

结论

TAP阻滞法的成本效益比非TAP法低20倍。因此,腹腔镜引导下的TAP阻滞可以低成本提供更好的术后镇痛,与超声引导下的TAP阻滞具有相似的优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf13/9801340/eea9a9f3f3a4/cureus-0014-00000032038-i01.jpg

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