Selvaraj Kaviya, Gayatri Devi R, Selvaraj J, Jothi Priya A
Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai 600077, India.
Bioinformation. 2022 Apr 30;18(4):331-336. doi: 10.6026/97320630018331. eCollection 2022.
(L.) is an annual herbaceous plant in the family Acanthaceae. Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. They are sometimes called "free-radical scavengers. Therefore, it is of interest to analyse the anti-inflammatory and antioxidant properties of and Andrographis paniculata. Protease inhibitor activity was done by bovine serum albumin was added to 100µl of plant sample with increase in concentrations (100-500µg/ml). Invitro antioxidant activity was done by DPPH free radical scavenging assay. 200 µL of 0.1 mM DPPH prepared in methanol was added to 100 µL of the plant extract with increase in concentration. Based on the results from the present study, it can be concluded that is found to be a good natural antioxidant source and is found to be a good anti-inflammatory source. However, both the plant and A.paniculata have these properties. Data shows that both and have potential anti-inflammatory and antioxidant activity which could be due to the presence of bioactive compounds present in the plant extracts.
(L.)是爵床科的一年生草本植物。抗炎是指一种物质或治疗方法具有减轻炎症或肿胀的特性。抗氧化剂是能够预防或减缓自由基对细胞造成损害的物质,自由基是身体在对环境及其他压力作出反应时产生的不稳定分子。它们有时被称为“自由基清除剂”。因此,分析(L.)和穿心莲的抗炎和抗氧化特性具有重要意义。蛋白酶抑制剂活性通过向100微升植物样品中添加牛血清白蛋白来测定,浓度逐渐增加(100 - 500微克/毫升)。体外抗氧化活性通过DPPH自由基清除试验来测定。将200微升用甲醇配制的0.1毫摩尔DPPH添加到100微升植物提取物中,浓度逐渐增加。根据本研究的结果,可以得出结论,(L.)被发现是一种良好的天然抗氧化剂来源,穿心莲被发现是一种良好的抗炎剂来源。然而,(L.)和穿心莲这两种植物都具有这些特性。数据表明,(L.)和穿心莲都具有潜在的抗炎和抗氧化活性,这可能是由于植物提取物中存在生物活性化合物。