The anti-inflammatory activity of the compounds isolated from leaves.

Lour. is a traditional medicinal herb that has been applied in the treatment of malaria and some other infectious diseases. Studies recently have focused on the anti-inflammation of the extracts of Lour. although there have not many reports about which compounds play the essential role. Therefore, in this study, we isolated hydrangenoside C (), isoarborinol (), and methyl 1,3,4,6-tetra-O-acetyl-fructofuranoside () from the leaves of . Subsequently, the anti-inflammatory property of - was assessed using an assay of edema mouse model which was induced by carrageenan. Out of the three, inhibited the edema effectively and dose-dependently, similarly to diclofenac while there was no obvious activity observed in and . The results demonstrated that enables binding to 5-LOX and PLA2 via generating h-bonds. This is the first study to mention the anti-inflammation of in Lour., and would be a contribution to further studies to elucidate the promising bioactivities of this compound.