Department of Radiology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, PR China.
Department of Thoracic Oncology, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, PR China.
Acta Radiol. 2023 Jun;64(6):2118-2125. doi: 10.1177/02841851231159389. Epub 2023 Mar 13.
Field-of-view optimized and constrained undistorted single-shot imaging (FOCUS) is a new sequence that shows enhanced anatomical details, improving the diffusion-weighted (DW) images.
To investigate the value of FOCUS diffusion-weighted imaging (DWI) in the evaluation of nasopharyngeal carcinoma (NPC) and compare it with the single-shot echo planner imaging (SS-EPI) DWI approach.
A total of 87 patients with NPC underwent magnetic resonance imaging, including FOCUS and SS-EPI DWI sequences. The signal-to-noise ratio (SNR), signal-intensity ratio (SIR), contrast-to-noise ratio (CNR), and apparent diffusion coefficient (ADC) values of the nasopharyngeal lesions were measured and compared. According to the clinical stages of patients, T and N were divided into early and advanced stage groups, respectively. The mean ADC values of the two techniques were computed, and the area under the curve (AUC) was estimated to calculate the diagnostic efficiency.
Subjective and objective image qualitative values of FOCUS were significantly higher than those of SS-EPI. The ADC values for FOCUS of early T and N stages were significantly lower than those of the advanced stages.
FOCUS provides significantly better image quality in NPC compared to SS-EPI, with lower ADC values for early-stage disease than late-stage disease.
视野优化和约束无失真单次激发成像（FOCUS）是一种新的序列，可增强解剖细节，改善扩散加权（DW）图像。
探讨 FOCUS 扩散加权成像（DWI）在鼻咽癌（NPC）评估中的价值，并将其与单次激发回波平面成像（SS-EPI）DWI 方法进行比较。
共 87 例 NPC 患者行磁共振成像检查，包括 FOCUS 和 SS-EPI DWI 序列。测量并比较鼻咽病变的信噪比（SNR）、信号强度比（SIR）、对比噪声比（CNR）和表观扩散系数（ADC）值。根据患者的临床分期，T 和 N 分别分为早期和晚期组。计算两种技术的平均 ADC 值，并计算曲线下面积（AUC）以计算诊断效率。
FOCUS 的主观和客观图像定性值明显高于 SS-EPI。早期 T 和 N 期 FOCUS 的 ADC 值明显低于晚期。
与 SS-EPI 相比，FOCUS 可为 NPC 提供明显更好的图像质量，早期疾病的 ADC 值低于晚期疾病。
