ZOOMit-DWI 序列与常规 DWI 序列在子宫内膜癌中的对比。
Comparison of ZOOMit-DWI sequence and conventional DWI sequence in endometrial cancer.
机构信息
Department of Radiology, Second Xiangya Hospital, Central South University, Changsha 410011.
Department of Obstetrics and Gynecology, Second Xiangya Hospital, Central South University, Changsha 410011.
出版信息
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 Jan 28;48(1):76-83. doi: 10.11817/j.issn.1672-7347.2023.220018.
OBJECTIVES
Magnetic resonance diffusion-weighted imaging (DWI) has important clinical value in diagnosis and curative effect evaluation on endometrial carcinoma. How to improve the detection rate of endometrial small lesions by DWI is the research focus of MRI technology. This study aims to analyze the image quality of small field MRI ZOOMit-DWI sequence and conventional single-shot echo-planar imaging (SS-EPI) DWI sequence in the scanning of endometrial carcinoma, and to explore the clinical value of ZOOMit-DWI sequence.
METHODS
A total of 37 patients with endometrial carcinoma diagnosed by operation and pathology in the Second Xiangya Hospital of Central South University from July 2019 to May 2021 were collected. All patients were scanned with MRI ZOOMit-DWI sequence and SS-EPI DWI sequence before operation. Two radiologists subjectively evaluated the anatomical details, artifacts, geometric deformation and focus definition of the 2 groups of DWI images. At the same time, the signal intensity were measured and the signal-to-noise ratio (SNR), contrast to noise ratio (CNR), and apparent diffusion coefficient (ADC) of the 2 DWI sequences were calculated for objective evaluation. The differences of subjective score, objective score and ADC value of the 2 DWI sequences were analyzed.
RESULTS
The SNR of the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (301.96±141.85 vs 94.66±41.26), and the CNR of the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (185.05±105.45 vs 57.91±31.54, P<0.05). There was no significant difference in noise standard deviation between the ZOOMit-DWI group and the SS-EPI DWI group (P>0.05). The subjective score of anatomical detail and focus definition in the ZOOMit-DWI group was significantly higher than that of the SS-EPI DWI group (both P<0.05). The subjective score of artifacts and geometric deformation of ZOOMit-DWI group was significantly lower than that of the SS-EPI DWI group (both P<0.05). ADC had no significant difference between the ZOOMit-DWI group and the SS-EPI DWI group (P>0.05).
CONCLUSIONS
The image quality of ZOOMit-DWI is significantly higher than that of conventional SS-EPI DWI. In the MRI DWI examination of endometrial carcinoma, ZOOMit-DWI can effectively reduce the geometric deformation and artifacts of the image, which is more conducive to clinical diagnosis and treatment.
目的
磁共振弥散加权成像（DWI）在子宫内膜癌的诊断和疗效评估中具有重要的临床价值。如何提高 DWI 对子宫内膜小病灶的检出率是 MRI 技术的研究重点。本研究旨在分析小视野 MRI ZOOMit-DWI 序列与常规单次激发平面回波成像（SS-EPI）DWI 序列在子宫内膜癌扫描中的图像质量，并探讨 ZOOMit-DWI 序列的临床价值。
方法
收集 2019 年 7 月至 2021 年 5 月在中南大学湘雅二医院经手术和病理诊断为子宫内膜癌的 37 例患者。所有患者均在术前接受 MRI ZOOMit-DWI 序列和 SS-EPI DWI 序列扫描。两位放射科医生对两组 DWI 图像的解剖细节、伪影、几何变形和焦点定义进行主观评估。同时，对两组 DWI 进行信号强度测量，计算信噪比（SNR）、对比噪声比（CNR）和表观扩散系数（ADC）进行客观评价。分析两组 DWI 序列的主观评分、客观评分和 ADC 值的差异。
结果
ZOOMit-DWI 组的 SNR 明显高于 SS-EPI DWI 组（301.96±141.85 比 94.66±41.26），ZOOMit-DWI 组的 CNR 明显高于 SS-EPI DWI 组（185.05±105.45 比 57.91±31.54，P<0.05）。ZOOMit-DWI 组与 SS-EPI DWI 组的噪声标准差差异无统计学意义（P>0.05）。ZOOMit-DWI 组在解剖细节和焦点定义方面的主观评分明显高于 SS-EPI DWI 组（均 P<0.05）。ZOOMit-DWI 组在伪影和几何变形方面的主观评分明显低于 SS-EPI DWI 组（均 P<0.05）。ZOOMit-DWI 组与 SS-EPI DWI 组的 ADC 值差异无统计学意义（P>0.05）。
结论
ZOOMit-DWI 的图像质量明显优于常规 SS-EPI DWI。在子宫内膜癌的 MRI DWI 检查中，ZOOMit-DWI 能有效降低图像的几何变形和伪影，更有利于临床诊断和治疗。
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