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F-2-脱氧-2-氟-D-葡萄糖正电子发射断层扫描/计算机断层扫描在猫甲状腺癌分期中的应用。

Use of F-2-deoxy-2-fluoro-D-glucose positron emission tomography/computed tomography for staging thyroid carcinoma in a cat.

机构信息

Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea.

出版信息

Vet Med Sci. 2023 May;9(3):1026-1030. doi: 10.1002/vms3.1106. Epub 2023 Mar 13.

Abstract

Thyroid nodules are common in older cats and are mostly benign; however, carcinomas may occur infrequently. In cats, thyroid carcinomas tend to be highly metastatic. The role of F-2-deoxy-2-fluoro-D-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) in human thyroid carcinoma has been well established. However, guidelines have not yet been established for veterinary medicine. Metastasis assessment has typically been performed using CT in veterinary medicine; however, it is poorly sensitive in detecting regional lymph nodes or distant metastases if these lesions are not abnormally contrast-enhanced, enlarged or cause overt mass effects. This case suggested that FDG PET/CT may be used for staging feline thyroid carcinoma, and the results contributed to treatment recommendations.

摘要

甲状腺结节在老年猫中很常见,大多为良性;然而,癌也可能罕见发生。在猫中,甲状腺癌往往具有高度转移性。 F-2-脱氧-2-氟-D-葡萄糖(FDG)正电子发射断层扫描(PET)/计算机断层扫描(CT)在人类甲状腺癌中的作用已经得到充分证实。然而,兽医领域尚未制定相关指南。在兽医领域,转移评估通常使用 CT 进行;然而,如果这些病变没有异常增强、增大或引起明显的肿块效应,其对检测区域淋巴结或远处转移的敏感性较差。本病例提示 FDG PET/CT 可用于分期猫甲状腺癌,且结果有助于治疗建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc00/10188059/df8caeb401d3/VMS3-9-1026-g003.jpg

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