Branco Tiago, Marques Catarina, Santos Vera C, Lopes João M
Serviço de Medicina 2, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisboa, PRT.
Internal Medicine, Hospital José Joaquim Fernandes, Beja, PRT.
Cureus. 2023 Feb 9;15(2):e34797. doi: 10.7759/cureus.34797. eCollection 2023 Feb.
Gradenigo's syndrome (GS) is a rare but life-threatening complication of acute otitis media (AOM). It is classically defined as a clinical triad of acute otitis media, ipsilateral sixth (abducens) nerve palsy, and pain in the distribution of the first and second branches of the trigeminal nerve. Another rare but serious complication of AOM is venous sinus thrombosis, which is often associated with GS. The diagnosis of these conditions requires clinical suspicion, sound interpretation of signs and symptoms, and the use of the correct imaging techniques. Here, we present the case of an 81-year-old man with a previous history of recurrent otitis media, who presented with GS and septic lateral sinus thrombosis. The clinical presentation, physiopathology, and management of these conditions are discussed.
格拉代尼戈综合征(GS)是急性中耳炎(AOM)一种罕见但危及生命的并发症。它经典地被定义为急性中耳炎、同侧第六(展)神经麻痹以及三叉神经第一和第二分支分布区域疼痛的临床三联征。AOM的另一种罕见但严重的并发症是静脉窦血栓形成,其常与GS相关。这些病症的诊断需要临床怀疑、对体征和症状的合理解读以及正确成像技术的使用。在此,我们报告一例81岁男性患者,既往有复发性中耳炎病史,此次表现为GS和化脓性外侧窦血栓形成。并对这些病症的临床表现、病理生理学及治疗进行了讨论。