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与急性中耳炎相关的迟发性诊断Gradenigo综合征。

Delayed diagnosed Gradenigo's syndrome associated with acute otitis media.

作者信息

Demir Berat, Abuzaid Ghazi, Ergenc Zeynep, Kepenekli Eda

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Pendik Training and Research Hospital, Marmara University Medical Faculty, Istanbul, Turkey.

Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.

出版信息

SAGE Open Med Case Rep. 2020 Oct 20;8:2050313X20966119. doi: 10.1177/2050313X20966119. eCollection 2020.

DOI:10.1177/2050313X20966119
PMID:33194201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7594227/
Abstract

Gradenigo's syndrome presents as a triad of retroorbital pain, ipsilateral abducens palsy, and purulent otorrhea. If the otologic pathologies in Gradenigo's syndrome go unnoticed, the condition could be misdiagnosed with neurological diseases because of retroorbital pain and abducens palsy. Treatment of Gradenigo's syndrome remains controversial. Although some reports state that long-term antibiotic treatment is sufficient, we recommended that management ought to be guided on a case-by-case basis depending on patient and disease factors. Herein, we report a delayed diagnosed pediatric case of Gradenigo's syndrome associated with acute otitis media that was treated with ventilation tube insertion.

摘要

Gradenigo综合征表现为眶后疼痛、同侧展神经麻痹和脓性耳漏三联征。如果Gradenigo综合征中的耳科病变未被注意到,由于眶后疼痛和展神经麻痹,该病症可能会被误诊为神经系统疾病。Gradenigo综合征的治疗仍存在争议。尽管一些报告称长期抗生素治疗就足够了,但我们建议应根据患者和疾病因素,逐案指导治疗。在此,我们报告一例与急性中耳炎相关的Gradenigo综合征的儿科延迟诊断病例,该病例通过插入通气管进行治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/b6fce32344b7/10.1177_2050313X20966119-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/d15fee813930/10.1177_2050313X20966119-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/547f3a54853a/10.1177_2050313X20966119-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/b6fce32344b7/10.1177_2050313X20966119-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/d15fee813930/10.1177_2050313X20966119-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/547f3a54853a/10.1177_2050313X20966119-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d100/7594227/b6fce32344b7/10.1177_2050313X20966119-fig3.jpg

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本文引用的文献

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J Laryngol Otol. 2019 Jun;133(6):535-537. doi: 10.1017/S0022215119001026. Epub 2019 May 28.
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Acute otitis media associated with Gradenigo syndrome and transverse sinus thrombosis: a case report.急性中耳炎合并Gradenigo综合征及横窦血栓形成:一例报告
J Int Med Res. 2019 Mar;47(3):1348-1352. doi: 10.1177/0300060518823404. Epub 2019 Jan 22.
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Gradenigo Syndrome Induced by Suppurative Otitis Media.
Gradenigo综合征和Vernet综合征作为鼻咽癌的首发症状
Cureus. 2023 Jul 10;15(7):e41636. doi: 10.7759/cureus.41636. eCollection 2023 Jul.
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Gradenigo's syndrome presenting as IX and X cranial nerve palsy without clinically apparent ear infection: A case report and review of literature.以Ⅸ和Ⅹ颅神经麻痹为表现且无明显耳部感染的Gradenigo综合征:一例病例报告及文献复习
eNeurologicalSci. 2022 Mar 17;27:100397. doi: 10.1016/j.ensci.2022.100397. eCollection 2022 Jun.
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BMJ Case Rep. 2021 Jul 13;14(7):e244401. doi: 10.1136/bcr-2021-244401.
化脓性中耳炎所致Gradenigo综合征
J Craniofac Surg. 2018 Oct;29(7):e645-e646. doi: 10.1097/SCS.0000000000004660.
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Laryngoscope. 2018 Jan;128(1):195-201. doi: 10.1002/lary.26571. Epub 2017 Apr 5.
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Petrositis With Bilateral Abducens Nerve Palsies complicated by Acute Otitis Media.伴有双侧展神经麻痹的 Petrositis 合并急性中耳炎。
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