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Excretion of oxazepam in breast milk.

作者信息

Wretlind M

机构信息

KabiVitrum AB, Research and Development Laboratories, Stockholm, Sweden.

出版信息

Eur J Clin Pharmacol. 1987;33(2):209-10. doi: 10.1007/BF00544570.

DOI:10.1007/BF00544570
PMID:3691611
Abstract

Oxazepam was measured in plasma and breast milk during 3 days of medication and 10 and 34 h after the last dose. The half-life estimated from levels in plasma and milk was approximately 12 hours. Less than 1/1000 of the maternal dose would have been excreted in 1 l breast milk.

摘要

相似文献

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Excretion of oxazepam in breast milk.
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本文引用的文献

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Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.苯二氮䓬类药物在妊娠、分娩和哺乳期的使用，特别涉及药代动力学方面的考量。
Drugs. 1982 May;23(5):354-80. doi: 10.2165/00003495-198223050-00002.
2
Determination of oxazepam in serum and urine by electron capture gas chromatography.
Acta Pharm Suec. 1972 Nov;9(5):447-56.
3
An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometry.
J Pharm Pharmacol. 1973 May;25(5):387-93. doi: 10.1111/j.2042-7158.1973.tb10033.x.
4
哺乳期使用精神药物治疗情绪障碍：实用建议
CNS Drugs. 2006;20(3):187-98. doi: 10.2165/00023210-200620030-00002.
4
A guide to the safety of CNS-active agents during breastfeeding.哺乳期使用中枢神经系统活性药物的安全性指南。
Drug Saf. 1997 Aug;17(2):127-42. doi: 10.2165/00002018-199717020-00005.
5
Pharmacokinetics in lactating women: prediction of alprazolam transfer into milk.哺乳期妇女的药代动力学：阿普唑仑向乳汁转移的预测。
Br J Clin Pharmacol. 1995 Sep;40(3):231-6. doi: 10.1111/j.1365-2125.1995.tb05778.x.
6
Excretion of psychoactive drugs into breast milk. Pharmacokinetic principles and recommendations.精神活性药物在母乳中的排泄。药代动力学原理与建议。
Clin Pharmacokinet. 1994 Oct;27(4):270-89. doi: 10.2165/00003088-199427040-00003.
7
Zolpidem excretion in breast milk.唑吡坦在母乳中的排泄情况。
Eur J Clin Pharmacol. 1989;37(3):245-8. doi: 10.1007/BF00679778.
8
Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.在停用高剂量地西泮和奥沙西泮联合用药期间，地西泮及其代谢产物在人乳中的排泄情况。
Br J Clin Pharmacol. 1990 Jan;29(1):123-6. doi: 10.1111/j.1365-2125.1990.tb03612.x.
9
Excretion of temazepam in breast milk.替马西泮在母乳中的排泄情况。
Br J Clin Pharmacol. 1992 Feb;33(2):204-6. doi: 10.1111/j.1365-2125.1992.tb04029.x.
Placental passage of oxazepam and its metabolism in mother and newborn.奥沙西泮的胎盘转运及其在母婴体内的代谢
Clin Pharmacol Ther. 1979 Jan;25(1):74-81. doi: 10.1002/cpt197925174.
5
[Oxazepam withdrawal in the neonatal period].[新生儿期的奥沙西泮戒断]
Lakartidningen. 1979 Nov 28;76(48):4416-7.
6
Pharmacokinetics of oxazepam in healthy volunteers.奥沙西泮在健康志愿者中的药代动力学。
Acta Pharmacol Toxicol (Copenh). 1977 Jan;40 Suppl 1(1):40-51.
7
Benzodiazepine activity: is interaction with the glycine receptor, as evidenced by displacement of strychnine binding, a useful criterion?
J Pharm Pharmacol. 1977 Jul;29(7):442-4. doi: 10.1111/j.2042-7158.1977.tb11363.x.
8
Disposition of three benzodiazepines after single oral administration in man.三种苯二氮䓬类药物单次口服给药后在人体中的处置情况。
Acta Pharmacol Toxicol (Copenh). 1977 Jan;40 Suppl 1(1):28-39.