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用于伤口治疗的海藻酸盐水凝胶的合成与发展综述。

A review on the synthesis and development of alginate hydrogels for wound therapy.

作者信息

Cao Yang, Cong Hailin, Yu Bing, Shen Youqing

机构信息

College of Chemistry and Chemical Engineering, College of Materials Science and Engineering, Institute of Biomedical Materials and Engineering, Qingdao University, Qingdao, 266071, China.

State Key Laboratory of Bio-Fibers and Eco-Textiles, Qingdao University, Qingdao 266071, China.

出版信息

J Mater Chem B. 2023 Mar 30;11(13):2801-2829. doi: 10.1039/d2tb02808e.

DOI:10.1039/d2tb02808e
PMID:36916313
Abstract

Convenient and low-cost dressings can reduce the difficulty of wound treatment. Alginate gel dressings have the advantages of low cost and safe usage, and they have obvious potential for development in biomedical materials. Alginate gel dressings are currently a research area of great interest owing to their versatility, intelligent, and their application attempts in treating complex wounds. We present a detailed summary of the preparation of alginate hydrogels and a study of their performance improvement. Herein, we summarize the various applications of alginate hydrogels. The research focuses in this area mainly include designing multifunctional dressings for the treatment of various wounds and fabricating specialized dressings to assist physicians in the treatment of complex wounds (TOC). This review gives an outlook for future directions in the field of alginate hydrogel dressings. We hope to attract more research interest and studies in alginate hydrogel dressings, thus contributing to the creation of low-cost and highly effective wound treatment materials.

摘要

方便且低成本的敷料可以降低伤口治疗的难度。藻酸盐凝胶敷料具有成本低和使用安全的优点,在生物医学材料领域具有明显的发展潜力。藻酸盐凝胶敷料因其多功能性、智能性以及在治疗复杂伤口方面的应用尝试,目前是一个备受关注的研究领域。我们详细总结了藻酸盐水凝胶的制备及其性能改进研究。在此,我们总结了藻酸盐水凝胶的各种应用。该领域的研究重点主要包括设计用于治疗各种伤口的多功能敷料以及制造专门的敷料以协助医生治疗复杂伤口(TOC)。本综述展望了藻酸盐凝胶敷料领域的未来发展方向。我们希望吸引更多对藻酸盐凝胶敷料的研究兴趣和研究,从而有助于开发低成本且高效的伤口治疗材料。

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