Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
J Am Geriatr Soc. 2023 Aug;71(8):2441-2450. doi: 10.1111/jgs.18327. Epub 2023 Mar 14.
Orthopedists and other clinicians assess recovery potential of hip fracture patients at 2 months post-fracture for care planning. It is unclear if examining physical performance (e.g., balance, gait speed, chair stand) during this follow-up visit can identify individuals at a risk of poor functional recovery, especially mobility, beyond available information from medical records and self-report.
Data came from 162 patients with hip fracture enrolled in the Baltimore Hip Studies-7th cohort. Predictors of mobility status (ability to walk 1 block at 12 months post-fracture) were the Short Physical Performance Battery (SPPB) comprising balance, walking and chair rise tasks at 2 months; baseline medical chart information (sex, age, American Society of Anesthesiologist physical status rating, type of fracture and surgery, and comorbidities); and self-reported information about the physical function (ability to walk 10 feet and 1 block at pre-fracture and at 2 months post-fracture). Prediction models of 12-month mobility status were built using two methods: (1) logistic regression with least absolute shrinkage and selection operator (LASSO) regularization, and (2) classification and regression trees (CART). Area under ROC curves (AUROC) assessed discrimination.
The participants had a median age of 82 years, and 49.3% (n = 80) were men. Two-month SPPB and gait speed were selected as predictors of 12-month mobility by both methods. Compared with an analytic model with medical chart and self-reported information, the model that additionally included physical performance measures had significantly better discrimination for 12-month mobility (AUROC 0.82 vs. 0.88, p = 0.004).
Assessing SPPB and gait speed at 2 months after a hip fracture in addition to information from medical records and self-report significantly improves prediction of 12-month mobility. This finding has important implications in providing tailored clinical care to patients at a greater risk of being functionally dependent who would not otherwise be identified using regularly measured clinical markers.
骨科医生和其他临床医生在骨折后 2 个月评估髋部骨折患者的康复潜力,以制定护理计划。目前尚不清楚在随访时检查身体机能(如平衡、步态速度、坐站)是否可以识别出那些在可利用的病历和自我报告之外存在功能恢复不良风险(尤其是活动能力)的个体。
本研究数据来自巴尔的摩髋部研究-7 队列中的 162 名髋部骨折患者。采用 2 个月时的短体适能测试(Short Physical Performance Battery,SPPB)中平衡、行走和坐起任务来预测 12 个月时的移动状态(骨折后 12 个月时能否行走 1 个街区),同时预测模型还包括基线病历信息(性别、年龄、美国麻醉医师协会身体状况评分、骨折类型和手术类型以及合并症)和骨折前及骨折后 2 个月时的自我报告身体功能(能否行走 10 英尺和 1 个街区)。使用两种方法构建 12 个月移动状态的预测模型:(1)最小绝对值收缩和选择算子(least absolute shrinkage and selection operator,LASSO)正则化逻辑回归,和(2)分类和回归树(classification and regression trees,CART)。ROC 曲线下面积(area under the receiver operating characteristic curve,AUROC)评估了区分度。
参与者的中位年龄为 82 岁,49.3%(n=80)为男性。两种方法均选择 2 个月时的 SPPB 和步态速度作为 12 个月时移动能力的预测指标。与包含病历和自我报告信息的分析模型相比,另外包含身体机能测量指标的模型对 12 个月时的移动能力具有显著更好的区分度(AUROC 0.82 比 0.88,p=0.004)。
在髋部骨折后 2 个月时评估 SPPB 和步态速度,以及病历和自我报告信息,可显著提高对 12 个月时移动能力的预测。这一发现对于为那些在可利用的临床标志物之外存在功能依赖风险的患者提供个性化临床护理具有重要意义。