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BnIR:一个具有多种工具的多组学数据库,用于甘蓝型油菜的研究和育种。

BnIR: A multi-omics database with various tools for Brassica napus research and breeding.

作者信息

Yang Zhiquan, Wang Shengbo, Wei Lulu, Huang Yiming, Liu Dongxu, Jia Yupeng, Luo Chengfang, Lin Yuchen, Liang Congyuan, Hu Yue, Dai Cheng, Guo Liang, Zhou Yongming, Yang Qing-Yong

机构信息

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, China; Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan 430070, China; Innovative Center of Molecular Genetics and Evolution, School of Life Sciences, Guangzhou University, Guangzhou 510405, China.

National Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan 430070, China; Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.

出版信息

Mol Plant. 2023 Apr 3;16(4):775-789. doi: 10.1016/j.molp.2023.03.007. Epub 2023 Mar 14.

Abstract

In the post-genome-wide association study era, multi-omics techniques have shown great power and potential for candidate gene mining and functional genomics research. However, due to the lack of effective data integration and multi-omics analysis platforms, such techniques have not still been applied widely in rapeseed, an important oil crop worldwide. Here, we report a rapeseed multi-omics database (BnIR; http://yanglab.hzau.edu.cn/BnIR), which provides datasets of six omics including genomics, transcriptomics, variomics, epigenetics, phenomics, and metabolomics, as well as numerous "variation-gene expression-phenotype" associations by using multiple statistical methods. In addition, a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets. BnIR is the most comprehensive multi-omics database for rapeseed so far, and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms.

摘要

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