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一名新冠肺炎患者的胃曲霉菌病

Gastric Aspergillosis in a COVID-19 Patient.

作者信息

Hinojosa Valeria, Cesena De la Fuente Sabina, Hussaini Najia, Varon Joseph

机构信息

Research, Universidad Autónoma de Baja California, Tijuana, MEX.

Research, Caribbean Medical University, Houston, USA.

出版信息

Cureus. 2023 Feb 12;15(2):e34897. doi: 10.7759/cureus.34897. eCollection 2023 Feb.

DOI:10.7759/cureus.34897
PMID:36925984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10013252/
Abstract

The SARS-CoV-2 virus, which causes Coronavirus-19 infection (COVID-19), frequently elicits the development of depressed immunity, therefore, opportunistic infections. Opportunistic organisms are commonly present in the human body without causing critical illness. However, they can also lead to pathologic illness when a person is immunocompromised. Aspergillosis is among the many opportunistic infections. Even though this infection primarily involves the respiratory system and is less likely to be found in the gastrointestinal tract, we report a case of a COVID-19 individual that developed massive gastrointestinal bleeding whose condition deteriorated, and the pathological examination revealed gastric aspergillosis. Although not common, gastric aspergillosis should be considered while treating patients with COVID-19 who present gastrointestinal symptoms.

摘要

导致冠状病毒病-19感染(COVID-19)的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒经常引发免疫抑制,进而导致机会性感染。机会性微生物通常存在于人体中而不引起严重疾病。然而,当一个人的免疫功能受损时,它们也会导致病理性疾病。曲霉病是众多机会性感染之一。尽管这种感染主要累及呼吸系统,在胃肠道中较少见,但我们报告了一例COVID-19患者,该患者出现大量胃肠道出血,病情恶化,病理检查显示为胃曲霉病。虽然不常见,但在治疗出现胃肠道症状的COVID-19患者时应考虑胃曲霉病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/4f1e6359eea3/cureus-0015-00000034897-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/b4769a305595/cureus-0015-00000034897-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/07bc13abdeb3/cureus-0015-00000034897-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/4f1e6359eea3/cureus-0015-00000034897-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/b4769a305595/cureus-0015-00000034897-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/07bc13abdeb3/cureus-0015-00000034897-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29d1/10013252/4f1e6359eea3/cureus-0015-00000034897-i03.jpg

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A scoping review of the pathophysiology of COVID-19.COVID-19 病理生理学的范围性综述。
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Curr Opin Crit Care. 2019 Oct;25(5):430-437. doi: 10.1097/MCC.0000000000000637.
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Difficult diagnosis of invasive fungal infection predominantly involving the lower gastrointestinal tract in acute lymphoblastic leukaemia.急性淋巴细胞白血病中主要累及下消化道的侵袭性真菌感染的诊断困难。
Med Mycol Case Rep. 2016 Jan 30;11:1-4. doi: 10.1016/j.mmcr.2016.01.005. eCollection 2016 Mar.
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Immunol Invest. 2011;40(7-8):751-66. doi: 10.3109/08820139.2011.614307.