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当前猴痘疫情的流行情况、诊断方法及防控措施综述。

Review of the prevalence, diagnostics, and containment measures of the current mpox outbreak.

作者信息

Sanyaolu Adekunle, Marinkovic Aleksandra, Okorie Chuku, Prakash Stephanie, Haider Nafees, Dixon Yashika, Izurieta Ricardo, Badaru Olanrewaju, Smith Stella

机构信息

Public Health, Federal Ministry of Health, Abuja 083, Federal Capital Territory, Nigeria.

Basic Science, Saint James School of Medicine, The Quarter 2640, Anguilla.

出版信息

World J Clin Cases. 2023 Feb 26;11(6):1252-1260. doi: 10.12998/wjcc.v11.i6.1252.

DOI:10.12998/wjcc.v11.i6.1252
PMID:36926120
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10013105/
Abstract

Monkeypox (mpox), is a disease from the family that can cause several serious medical issues. This mini-review sought to analyze the existing literature regarding the current mpox outbreak with a focus on the prevalence, diagnostics, and containment measures. Mpox cases have been reported to World Health Organization (WHO) from 85 Member States in all six WHO regions during the period of January 1, 2022, through August 3, 2022. Standardized or optimized guidelines for the clinical care of patients with mpox are limited, particularly in low-resource settings. In an effort to achieve guidance and meet standards, special attention should be paid to this outbreak in order to eradicate such a rare infectious disease by analyzing prevention and control measures. Patient outcomes may also be poor, and their illnesses may last for a long time. The spectrum of clinical symptoms, including complications and sequelae, as well as aspects of the illness may be indicators of sickness severity and complications; therefore, its clinical presentation must be better understood to improve containment measures. In addition, it is important to create and evaluate a standard of care that takes a variety of parameters into account, including antiviral, immune therapies, and clinical metrics that are particular to mpox. The global emergence of mpox has presented new challenges for public health and has called for further investigation into its epidemiological profile across international contexts.

摘要

猴痘是一种可引发多种严重医学问题的疾病。本综述旨在分析有关当前猴痘疫情的现有文献,重点关注其流行情况、诊断方法及防控措施。在2022年1月1日至2022年8月3日期间,世界卫生组织(WHO)的所有六个区域的85个成员国均已向其报告了猴痘病例。针对猴痘患者的临床护理,标准化或优化的指南较为有限,在资源匮乏地区尤其如此。为了获得指导并达到标准,应特别关注此次疫情,通过分析预防和控制措施来根除这种罕见的传染病。患者的预后可能也较差,且疾病可能持续较长时间。临床症状谱,包括并发症和后遗症,以及疾病的各个方面可能是疾病严重程度和并发症的指标;因此,必须更好地了解其临床表现,以改进防控措施。此外,制定并评估一种考虑多种参数的护理标准很重要,这些参数包括抗病毒治疗、免疫疗法以及猴痘特有的临床指标。猴痘在全球范围内的出现给公共卫生带来了新挑战,需要进一步调查其在国际背景下的流行病学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fe/10013105/958343ffe6d4/WJCC-11-1252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fe/10013105/96ef84a23f5c/WJCC-11-1252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fe/10013105/958343ffe6d4/WJCC-11-1252-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fe/10013105/96ef84a23f5c/WJCC-11-1252-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70fe/10013105/958343ffe6d4/WJCC-11-1252-g002.jpg

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本文引用的文献

1
Monkeypox: A Mini-Review on the Globally Emerging Orthopoxvirus.猴痘:一种全球新兴的正痘病毒的综述。
Int J Environ Res Public Health. 2022 Nov 25;19(23):15684. doi: 10.3390/ijerph192315684.
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Monkeypox: A Comprehensive Review.猴痘:全面综述。
Viruses. 2022 Sep 29;14(10):2155. doi: 10.3390/v14102155.
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Prevention of monkeypox with vaccines: a rapid review.疫苗预防猴痘:快速综述。
Lancet Infect Dis. 2022 Dec;22(12):e349-e358. doi: 10.1016/S1473-3099(22)00574-6. Epub 2022 Sep 15.
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Comparison of Transcriptomic Signatures between Monkeypox-Infected Monkey and Human Cell Lines.猴痘感染的猴和人细胞系转录组特征比较。
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Clin Immunol. 2022 Oct;243:109108. doi: 10.1016/j.clim.2022.109108. Epub 2022 Sep 5.
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Comparative Pathology of Zoonotic Orthopoxviruses.人畜共患正痘病毒的比较病理学
Pathogens. 2022 Aug 9;11(8):892. doi: 10.3390/pathogens11080892.
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Monkeypox during COVID-19 era in Africa: Current challenges and recommendations.非洲新冠疫情时代的猴痘:当前挑战与建议
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Monkeypox: A Review of Clinical Features, Diagnosis, and Treatment.猴痘:临床特征、诊断与治疗综述
Cureus. 2022 Jul 11;14(7):e26756. doi: 10.7759/cureus.26756. eCollection 2022 Jul.
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Monkeypox virus outbreak: can evolution guide us to new treatments or vaccines?猴痘病毒爆发:进化能引导我们找到新的治疗方法或疫苗吗?
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