Clinical course of an exacerbated pulmonary infection in a girl with cystic fibrosis (CF).

The treatment of severe pulmonary infection in young CF-adults depends on age, clinical course, bacterial colonization of the lung, susceptibility pattern and state of nutrition. Besides specific antibiotic therapy, enzyme replacement and physiotherapy, high caloric nutrition, continuous oxygen insufflation and early mobilisation are the main tools in the treatment of an exacerbated pulmonary infection with respiratory insufficiency.