Institute of Social Medicine, Epidemiology and Health Economics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Centre for Integrative Health, London, United Kingdom.
J Integr Complement Med. 2023 May;29(5):327-333. doi: 10.1089/jicm.2022.0755. Epub 2023 Mar 17.
This is a 54-year-old woman from Germany of central European origin who developed an acute hepatitis while orally taking Ayurvedic herbal remedies, among those was the medicinal herb . She took the plant powders from July 1, 2021, to October 1, 2021, with the intention of relieving the symptoms of her subjectively irritated gastrointestinal tract. The patient's main symptoms of acute hepatitis were progressively increasing general fatigue, nausea, and exhaustion. During an inpatient hospital admission from November 4, 2021, to November 9, 2021, she was under clinical observation, but no specific therapeutic measures were deemed necessary; however, blood chemistry showed an acute toxic hepatitis. There was no clinical or laboratory evidence of acute liver failure. Aminotransferase values decreased to normal values on December 14, 2021, by themselves. This case report contributes to the ongoing discussion about the potential risks of triggering an acute hepatitis due to the intake of herbal remedies from the genus in rare cases, differentiating other involved risk factors. The case also shows that causality assignments are not trivial in the context of multivariate clinical scenarios. In the case of known hepatic metabolism-associated risk factors, should be used with more caution based on available case reports. At the same time, no hasty and exaggerated prejudgments should be made about this medicinal herb, which has been very successfully used in traditional South Asian systems of medicine for many centuries.
这是一位来自德国的 54 岁女性，具有中欧血统，在口服印度草药治疗期间出现急性肝炎，其中包括药用植物 。她于 2021 年 7 月 1 日至 10 月 1 日服用这些植物粉末，目的是缓解主观上感到肠胃不适的症状。患者急性肝炎的主要症状是逐渐加重的全身乏力、恶心和疲惫。2021 年 11 月 4 日至 11 月 9 日住院期间，她接受了临床观察，但认为没有必要采取具体的治疗措施；然而，血液化学显示急性毒性肝炎。没有临床或实验室证据表明急性肝衰竭。2021 年 12 月 14 日，氨基转移酶值自行降至正常值。本病例报告有助于继续讨论由于摄入该属的草药，在极少数情况下可能引发急性肝炎的潜在风险，同时区分其他相关的风险因素。该病例还表明，在多因素临床情况下，因果关系的确定并不简单。在已知与肝代谢相关的风险因素的情况下，根据现有病例报告，应更加谨慎地使用 。同时，对于这种在传统南亚医学体系中已成功使用了数百年的草药，不应仓促做出过分夸大的判断。
