Jouha Jabrane, Li Fengli, Xiong Hai
Institute for Advanced Study, Shenzhen University, Shenzhen 518060, PR China.
Institute for Advanced Study, Shenzhen University, Shenzhen 518060, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jul 5;295:122615. doi: 10.1016/j.saa.2023.122615. Epub 2023 Mar 12.
Due to their distinctive physical, chemical, electrical, and optical properties as well as their prospective uses, 2D covalent organic framework (COF) have attracted much attention. Herein, TaTPA-COF was effectively synthesized from the condensation of TTA and TFPA using a facile solvothermal method and characterized by SEM image, FT-IR spectra, and PXRD pattern. The generated bulk TaTPA-COF materials combined with DNA aptamers are utilized as the acceptor (quencher) for the highly sensitive and selective detection of adenosine 5'-triphosphate (ATP) and thrombin, with a novel fluorescence biosensing platform and a proof-of-concept application.
由于其独特的物理、化学、电学和光学性质以及潜在用途，二维共价有机框架（COF）已引起广泛关注。在此，通过简便的溶剂热法由TTA和TFPA缩合有效合成了TaTPA-COF，并通过扫描电子显微镜图像、傅里叶变换红外光谱和粉末X射线衍射图谱对其进行了表征。将生成的块状TaTPA-COF材料与DNA适体结合，用作新型荧光生物传感平台和概念验证应用中用于高灵敏度和选择性检测5'-三磷酸腺苷（ATP）和凝血酶的受体（猝灭剂）。
