外苍白球中非运动信号的细胞类型特异性处理。
Cell type-specific processing of non-motor signals in the external pallidum.
机构信息
Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
出版信息
Trends Neurosci. 2023 May;46(5):336-337. doi: 10.1016/j.tins.2023.03.002. Epub 2023 Mar 17.
Abstract
The external globus pallidus (GPe) regulates motor control. However, whether the GPe encodes non-motor information remains unclear. Two recent studies, by Johansson and Ketzef, and Katabi et al., provide in vivo evidence for GPe neuron processing of sensory stimulation and reward cues via a division of labor among its cell types.
摘要
苍白球外侧部（GPe）调节运动控制。然而，GPe 是否编码非运动信息尚不清楚。最近由 Johansson 和 Ketzef 以及 Katabi 等人进行的两项研究通过其细胞类型之间的分工提供了 GPe 神经元处理感觉刺激和奖励线索的体内证据。
相似文献
1
Cell type-specific processing of non-motor signals in the external pallidum.外苍白球中非运动信号的细胞类型特异性处理。
Trends Neurosci. 2023 May;46(5):336-337. doi: 10.1016/j.tins.2023.03.002. Epub 2023 Mar 17.
2
Sensory processing in external globus pallidus neurons.外苍白球神经元的感觉处理。
Cell Rep. 2023 Jan 31;42(1):111952. doi: 10.1016/j.celrep.2022.111952. Epub 2023 Jan 4.
3
Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.小白蛋白阳性神经元和Npas1阳性神经元是小鼠外侧苍白球中不同的神经元类别。
J Neurosci. 2015 Aug 26;35(34):11830-47. doi: 10.1523/JNEUROSCI.4672-14.2015.
4
Dichotomous organization of the external globus pallidus.外苍白球的二分组织。
Neuron. 2012 Jun 21;74(6):1075-86. doi: 10.1016/j.neuron.2012.04.027.
5
External segment of the globus pallidus in health and disease: Its interactions with the striatum and subthalamic nucleus.苍白球外部节段在健康与疾病中的作用：与纹状体和丘脑底核的相互作用。
Neurobiol Dis. 2024 Jan;190:106362. doi: 10.1016/j.nbd.2023.106362. Epub 2023 Nov 20.
6
Npas1-Nkx2.1 Neurons Are an Integral Part of the Cortico-pallido-cortical Loop.Npas1-Nkx2.1 神经元是皮质-苍白球-皮质环路的一个组成部分。
J Neurosci. 2020 Jan 22;40(4):743-768. doi: 10.1523/JNEUROSCI.1199-19.2019. Epub 2019 Dec 6.
7
Cell and circuit complexity of the external globus pallidus.外苍白球的细胞和回路复杂性。
Nat Neurosci. 2023 Jul;26(7):1147-1159. doi: 10.1038/s41593-023-01368-7. Epub 2023 Jun 19.
8
Classification of GABAergic neuron subtypes from the globus pallidus using wild-type and transgenic mice.利用野生型和转基因小鼠对苍白球中的 GABA 能神经元亚型进行分类。
J Physiol. 2018 Sep;596(17):4219-4235. doi: 10.1113/JP276079. Epub 2018 Jul 30.
9
Dysregulation of external globus pallidus-subthalamic nucleus network dynamics in parkinsonian mice during cortical slow-wave activity and activation.帕金森病小鼠皮层慢波活动和激活时苍白球-丘脑底核网络动力学失调。
J Physiol. 2020 May;598(10):1897-1927. doi: 10.1113/JP279232. Epub 2020 Apr 23.
10
Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.外苍白球中 GluN2C 型 NMDA 受体的易化增加了快速放电神经元的放电活动，并改善了半帕金森病模型小鼠的运动功能。
Neurobiol Dis. 2021 Mar;150:105254. doi: 10.1016/j.nbd.2021.105254. Epub 2021 Jan 6.
引用本文的文献
1
Whole Brain Monosynaptic Input of Distinct Neurons in the Globus Pallidus Externa.苍白球外侧不同神经元的全脑单突触输入
CNS Neurosci Ther. 2025 Jun;31(6):e70459. doi: 10.1111/cns.70459.
2
Pallidal prototypic neuron and astrocyte activities regulate flexible reward-seeking behaviors.苍白球原型神经元和星形胶质细胞的活动调节灵活的奖赏寻求行为。
bioRxiv. 2025 Feb 10:2025.02.10.637554. doi: 10.1101/2025.02.10.637554.
本文引用的文献
1
Sensory processing in external globus pallidus neurons.外苍白球神经元的感觉处理。
Cell Rep. 2023 Jan 31;42(1):111952. doi: 10.1016/j.celrep.2022.111952. Epub 2023 Jan 4.
2
Dichotomous activity and function of neurons with low- and high-frequency discharge in the external globus pallidus of non-human primates.非人灵长类动物外侧苍白球中低频和高频放电神经元的二分活动与功能
Cell Rep. 2023 Jan 31;42(1):111898. doi: 10.1016/j.celrep.2022.111898. Epub 2023 Jan 2.
3
Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns.苍白球神经元亚型在调节运动模式中的分离作用。
J Neurosci. 2021 May 5;41(18):4036-4059. doi: 10.1523/JNEUROSCI.2210-20.2021. Epub 2021 Mar 17.
4
Striatal Direct Pathway Targets Npas1 Pallidal Neurons.纹状体直接通路靶向 Npas1 苍白球神经元。
J Neurosci. 2021 May 5;41(18):3966-3987. doi: 10.1523/JNEUROSCI.2306-20.2021. Epub 2021 Mar 17.
5
Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits.不同苍白球通路导致不同帕金森病行为缺陷。
Nat Neurosci. 2021 Apr;24(4):504-515. doi: 10.1038/s41593-021-00810-y. Epub 2021 Mar 15.
6
A Disynaptic Circuit in the Globus Pallidus Controls Locomotion Inhibition.苍白球中的一个二突触回路控制运动抑制。
Curr Biol. 2021 Feb 22;31(4):707-721.e7. doi: 10.1016/j.cub.2020.11.019. Epub 2020 Dec 10.
7
Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo.体内外苍白球神经元亚群的差异突触传入。
Neuron. 2021 Feb 3;109(3):516-529.e4. doi: 10.1016/j.neuron.2020.11.006. Epub 2020 Nov 27.
8
Parvalbumin and Npas1 Pallidal Neurons Have Distinct Circuit Topology and Function.苍白球内的 Parvalbumin 和 Npas1 神经元具有不同的环路拓扑结构和功能。
J Neurosci. 2020 Oct 7;40(41):7855-7876. doi: 10.1523/JNEUROSCI.0361-20.2020. Epub 2020 Aug 31.
9
Cell-specific pallidal intervention induces long-lasting motor recovery in dopamine-depleted mice.细胞特异性苍白球干预可诱导多巴胺耗竭小鼠实现持久的运动恢复。
Nat Neurosci. 2017 Jun;20(6):815-823. doi: 10.1038/nn.4559. Epub 2017 May 8.
10
Distinct developmental origins manifest in the specialized encoding of movement by adult neurons of the external globus pallidus.不同的发育起源表现于外侧苍白球成年神经元对运动的特殊编码中。
Neuron. 2015 Apr 22;86(2):501-13. doi: 10.1016/j.neuron.2015.03.007. Epub 2015 Apr 2.
Zotero 插件