Metabolomics and Genomics Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Non-communicable Disease Research Center, Alborz University of Medical Sciences, Karaj, Islamic Republic of Iran.
Prim Care Diabetes. 2023 Jun;17(3):238-241. doi: 10.1016/j.pcd.2023.03.004. Epub 2023 Mar 14.
The study aim was to evaluate the effects of public lockdown during the covid-19 pandemic on glucose and metabolic parameters as well as body weight control in type 2 diabetic patients.
This study was conducted in two outpatient Diabetes Clinics and analyzed data available in database of Diabetes Clinic. Data related to a year before covid-19 pandemic and a year during covid-19 pandemic was collected from the database and analyzed. Patients with type 2 diabetes included in the analysis if they had referred to Diabetes Clinics both before and during covid-19 pandemic. Demographic information and data about metabolic status were collected from the records of previous outpatient Clinic visits and compared RESULTS: Finally 9440 patients with mean age of 61.08 ± 11.62 referred to Diabetes Clinics in both the year before and the year of the corona pandemic. Mean FBS and HbA1c in diabetes patients reduced significantly from 155.37 ± 62.93 and 7.97 ± 1.74 before pandemic, respectively to 138.77 ± 45.39 and 7.54 ± 1.34, respectively during covid-19 outbreak. During covid-19 pandemic, all metabolic parameters including glycemic and lipid profile (except for triglyceride) and BMI (body mass index) reduced significantly statistically, but, these changes were not clinically significant. However, triglyceride level increased statistically significantly but again it was not significant clinically.
During COVID-19 lockdown, glycemic and metabolic control of diabetes patients have improved significantly except for triglycerides.
本研究旨在评估新冠疫情期间公共封锁对 2 型糖尿病患者血糖和代谢参数以及体重控制的影响。
本研究在两个门诊糖尿病诊所进行,并分析了糖尿病诊所数据库中的可用数据。从数据库中收集了新冠疫情前一年和疫情期间的数据,并进行了分析。如果患者在新冠疫情前和疫情期间都曾到糖尿病诊所就诊,则将其纳入分析。从以往门诊就诊记录中收集了患者的人口统计学信息和代谢状况数据,并进行了比较。
最终,共有 9440 名平均年龄为 61.08±11.62 岁的 2 型糖尿病患者在新冠疫情前一年和疫情期间均到糖尿病诊所就诊。糖尿病患者的空腹血糖和糖化血红蛋白分别从疫情前的 155.37±62.93 和 7.97±1.74 显著降低至 138.77±45.39 和 7.54±1.34。在新冠疫情期间,所有代谢参数(除了甘油三酯)和 BMI(体重指数)均显著降低,但这些变化在临床上无显著意义。然而,甘油三酯水平在统计学上显著增加,但临床上仍无显著意义。
在 COVID-19 封锁期间,除了甘油三酯外,糖尿病患者的血糖和代谢控制显著改善。