Tian Xuekai, Li Dong, Zhao Xin, Xiao Zitong, Sun Jingchun, Yuan Tiantian, Wang Yongcheng, Zuo Xinhui, Yang Gongshe, Yu Taiyong
Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, Laboratory of Animal Fat Deposition and Muscle Development, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Qinghai Yufu Animal Husbandry Development Co., Ltd, Qinghai, China.
Front Microbiol. 2023 Mar 2;14:1116022. doi: 10.3389/fmicb.2023.1116022. eCollection 2023.
In pig production, reducing production costs and improving immunity are important. Grape pomace, a good agricultural by-product, has been thrown away as food waste for a long time. Recently, we found that it could be used as a new source of pig feed. We investigated the effect of grape pomace on inflammation, gut barrier function, meat quality, and growth performance in finishing pigs. Our results indicated that treatment samples showed a significant decrease in water loss, IL-1β, DAO, ROS, and MDA content ( < 0.05). IgA, IgG, IgM, CAT, T-AOC, SOD, and IFN-γ significantly increased compared with those in control samples ( < 0.05). Meanwhile, the relative mRNA expression of the tight junction protein occludin showed a significant difference ( < 0.05). Analysis of metagenomic sequencing indicated that grape pomace significantly decreased the relative abundance of and ( < 0.05). In summary, our results demonstrated that grape pomace could improve meat quality, alleviate inflammation, and decrease oxidative stress.
在生猪生产中，降低生产成本和提高免疫力至关重要。葡萄渣是一种优质的农业副产品，长期以来一直作为食物垃圾被丢弃。最近，我们发现它可以用作猪饲料的新来源。我们研究了葡萄渣对育肥猪炎症、肠道屏障功能、肉质和生长性能的影响。我们的结果表明，处理组样本的水分损失、白细胞介素-1β、二胺氧化酶、活性氧和丙二醛含量显著降低（<0.05）。与对照组样本相比，免疫球蛋白A、免疫球蛋白G、免疫球蛋白M、过氧化氢酶、总抗氧化能力、超氧化物歧化酶和干扰素-γ显著增加（<0.05）。同时，紧密连接蛋白闭合蛋白的相对mRNA表达存在显著差异（<0.05）。宏基因组测序分析表明，葡萄渣显著降低了[具体菌群名称1]和[具体菌群名称2]的相对丰度（<0.05）。总之，我们的结果表明，葡萄渣可以改善肉质、减轻炎症并降低氧化应激。
