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大网膜动静脉畸形与假性梅格斯综合征的罕见关联:病例报告及文献综述

A rare association of arteriovenous malformation of the omentum and pseudo-Meigs' syndrome: case report and scoping review of literature.

作者信息

Baazeem Mazin S, AlJumah Modhi M, AlSalim Norah F, AlMalki Salman

机构信息

Department of Obstetrics and Gynecology, Women Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia.

King Khalid University Hospital, King Saud University Medical City, Riyadh, Saudi Arabia.

出版信息

J Surg Case Rep. 2023 Mar 15;2023(3):rjad080. doi: 10.1093/jscr/rjad080. eCollection 2023 Mar.

DOI:10.1093/jscr/rjad080
PMID:36937799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10017075/
Abstract

Meigs' syndrome is defined as a secondary triad of ascites, pleural effusion and benign ovarian tumor, usually fibroma. While pseudo-Meigs' syndrome is a rare condition that is associated with benign ovarian tumor-other than fibroma-or even malignant. The case presented is a 40-year-old Saudi, nulliparous woman who was referred for precise diagnostic work-up as a case of huge pelvic-abdominal mass, tense ascites and pleural effusion. After further investigations cancer antigen-125 was found to be elevated. An abdominal CT scan revealed significant interval increase in the size of ascites, which cause huge abdominal distention, as well as a significant pleural effusion. Pathology of surgical specimens revealed a giant uterine leiomyoma, whereas the omentum excision surprisingly confirmed multiple disorganized arteries and veins, which resulted in omental arteriovenous malformation. To the best of our knowledge, this is the first reported case in the worldwide literature of two different rare conditions.

摘要

梅格斯综合征被定义为腹水、胸腔积液和良性卵巢肿瘤(通常为纤维瘤)组成的继发性三联征。而假性梅格斯综合征是一种罕见病症,与非纤维瘤的良性卵巢肿瘤甚至恶性肿瘤相关。所呈现的病例是一名40岁未生育的沙特女性,因巨大盆腔腹部肿块、大量腹水和胸腔积液被转诊进行精确诊断检查。进一步检查后发现癌抗原125升高。腹部CT扫描显示腹水大小显著增加,导致腹部极度膨隆,同时还有大量胸腔积液。手术标本病理显示为巨大子宫平滑肌瘤,而大网膜切除标本令人惊讶地证实有多处杂乱的动静脉,导致大网膜动静脉畸形。据我们所知,这是全球文献中首次报道的同时存在两种不同罕见病症的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/8eda95a41a72/rjad080f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/801c8467d3f4/rjad080f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/80d63f1fc788/rjad080f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/1ec455262295/rjad080f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/8eda95a41a72/rjad080f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/801c8467d3f4/rjad080f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/80d63f1fc788/rjad080f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/1ec455262295/rjad080f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34ec/10017075/8eda95a41a72/rjad080f4.jpg

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本文引用的文献

1
[Pseudo-Meigs syndrome secondary to ovarian serous cystadenoma].卵巢浆液性囊腺瘤继发假性梅格斯综合征
Pan Afr Med J. 2019 May 7;33:11. doi: 10.11604/pamj.2019.33.11.18128. eCollection 2019.
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Huge Primary Parasitic Leiomyoma in a Postmenopausal Lady: A Rare Presentation.一位绝经后女性的巨大原发性寄生性平滑肌瘤:一种罕见的表现。
Case Rep Obstet Gynecol. 2019 Apr 1;2019:7683873. doi: 10.1155/2019/7683873. eCollection 2019.
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Sudden, Unexpected Death Due to Pseudo-Meigs Syndrome: A Case Report and Review of the Literature.
Am J Forensic Med Pathol. 2019 Mar;40(1):89-93. doi: 10.1097/PAF.0000000000000438.
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Hydrothorax, ascites and an abdominal mass: not always signs of a malignancy - Three cases of Meigs' syndrome.胸腔积液、腹水和腹部肿块:并非总是恶性肿瘤的征象——三例梅格斯综合征病例
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New Treatment Approaches to Arteriovenous Malformations.动静脉畸形的新治疗方法
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Long-term survival in pseudo-Meigs' syndrome caused by ovarian metastases from colon cancer.结肠癌卵巢转移所致假性梅格斯综合征的长期生存情况
World J Surg Oncol. 2016 Nov 14;14(1):286. doi: 10.1186/s12957-016-1040-0.
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Arteriovenous malformations and other vascular malformation syndromes.动静脉畸形和其他血管畸形综合征。
Cold Spring Harb Perspect Med. 2013 Feb 1;3(2):a006635. doi: 10.1101/cshperspect.a006635.
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Ovarian granulosa cell tumor presenting as Meigs' syndrome with elevated CA125.
Korean J Intern Med. 2005 Mar;20(1):105-9. doi: 10.3904/kjim.2005.20.1.105.
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Pseudo-meigs syndrome: uterine leiomyoma with bladder attachment associated with ascites and hydrothorax - a rare case of a rare syndrome.假性梅格斯综合征:伴有膀胱附着的子宫平滑肌瘤合并腹水和胸腔积液——一种罕见综合征的罕见病例。
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Uterine leiomyoma causing massive ascites and left pleural effusion with elevated CA 125: a case report.子宫平滑肌瘤导致大量腹水和左侧胸腔积液伴CA 125升高:一例报告
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