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根据临床指南调查的老年心力衰竭患者很少:对患者记录的回顾性分析。

Few geriatric heart failure patients investigated according to clinical guidelines: a retrospective review of patient records.

机构信息

Department of Neurobiology, Care Sciences and Society, Division of Clinical geriatrics, Karolinska Institutet, Stockholm, Sweden.

Stiftelsen Stockholms Sjukhem, Mariebergsgatan 22, SE-112 19, Stockholm, Sweden.

出版信息

BMC Geriatr. 2023 Mar 21;23(1):155. doi: 10.1186/s12877-023-03773-w.

Abstract

BACKGROUND

Research on heart failure (HF) has often focused on younger patients. The aim of this study was to analyze extent of investigation and treatment among older patients prior to referral to inpatient geriatric care for worsening of HF.

METHODS

Data on etiology, ejection fraction (EF) by echocardiography (ECHO), level of functioning according to New York Heart Association (NYHA), analysis of N-terminal-pro-brain natriuretic peptide (NT-Pro-BNP), ongoing treatment, adherence to guidelines, and information from previous caregiver were collected from patient records prior to admission from a sample of 134 patients.

RESULTS

Few patients had been examined by a cardiologist (14%) during the year prior to referral. EF assessment had been performed in 78% (n = 105). The patients were categorized as having HF with reduced (HFrEF 28%), preserved (HFpEF 53%) or mid-range (HFmrEF 19%) EF. HFpEF patients had older EF assessments (mean 517 days) than those with HFrEF (385 days). In 61% (n = 82) at least one assessment with NT-Pro-BNP had been performed, being older among patients with HFpEF (290 days vs 16 days). There was a strong positive correlation (OR 4.9, p = 0.001) between having recent assessments of EF and NT-Pro-BNP (n = 30, 21%) and being presented with etiology in the referral, adjusted for EF, age, sex, and comorbidity. Among the HFrEF patients, 78% were treated with ACEI/ARB and BB according to ESC guidelines but reaching only half of target doses. In the HFpEF group the corresponding treatment was 46%. Among patients with EF ≤ 35% only 14% were treated with mineral receptor antagonists, ie low adherence to guidelines.

CONCLUSIONS

HF care in this population of older individuals showed deficiencies. There was little contact with cardiologists, lack of information of etiology in referrals and low adherence to treatment guidelines. Improving adherence to HF guidelines regarding investigation and treatment for HF in older people is therefore urgent and calls for more collaboration between specialists in cardiology and geriatric medicine.

摘要

背景

心力衰竭(HF)的研究通常集中在年轻患者身上。本研究的目的是分析在转至老年住院患者心力衰竭恶化之前,对老年患者进行的检查和治疗程度。

方法

从 134 例患者的住院记录中收集了病因、超声心动图(ECHO)射血分数(EF)、纽约心脏协会(NYHA)功能水平、N-末端-pro-脑利钠肽(NT-Pro-BNP)分析、正在进行的治疗、遵循指南的情况以及之前护理人员的信息。

结果

在转介前的一年中,很少有患者接受过心脏病专家的检查(14%)。78%(n=105)进行了 EF 评估。患者被分为射血分数降低(HFrEF 28%)、射血分数保留(HFpEF 53%)或射血分数中间范围(HFmrEF 19%)的心衰。HFpEF 患者的 EF 评估年龄较大(平均 517 天),而 HFrEF 患者的 EF 评估年龄较小(385 天)。在 61%(n=82)至少进行了一次 NT-Pro-BNP 评估,HFpEF 患者的评估年龄大于 HFrEF 患者(290 天比 16 天)。EF 和 NT-Pro-BNP 的近期评估(n=30,21%)与转诊中病因的呈现之间存在强烈的正相关(OR 4.9,p=0.001),校正 EF、年龄、性别和合并症后。在 HFrEF 患者中,根据 ESC 指南,78%接受 ACEI/ARB 和 BB 治疗,但仅达到目标剂量的一半。在 HFpEF 组中,相应的治疗为 46%。在 EF≤35%的患者中,只有 14%接受了矿物质受体拮抗剂治疗,即低遵医嘱率。

结论

在这一老年人群中,HF 护理存在不足。与心脏病专家的接触很少,转诊中缺乏病因信息,治疗指南的遵医嘱率低。因此,迫切需要提高老年人 HF 调查和治疗的 HF 指南的遵医嘱率,并呼吁心脏病学和老年医学专家之间加强合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca6f/10029212/76b80c01bf16/12877_2023_3773_Fig1_HTML.jpg

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