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超声心动图在射血分数保留型心力衰竭中的作用:我们对影像学有何需求?

The Role of Echocardiography in Heart Failure with Preserved Ejection Fraction: What Do We Want from Imaging?

机构信息

Department of Cardiovascular Medicine, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, MN 55906, USA.

Department of Cardiovascular Medicine, Mayo Clinic and Foundation, 200 First Street Southwest, Rochester, MN 55906, USA.

出版信息

Heart Fail Clin. 2019 Apr;15(2):241-256. doi: 10.1016/j.hfc.2018.12.004. Epub 2019 Feb 2.

DOI:10.1016/j.hfc.2018.12.004
PMID:30832815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6402610/
Abstract

Noninvasive imaging, particularly echocardiography, plays a central role in the evaluation for heart failure with preserved ejection fraction (HFpEF). Echocardiography helps to rule in HFpEF among patients with unexplained dyspnea when the diagnosis is uncertain. In established HFpEF, echocardiography provides important insights into pathophysiology and phenotyping, such as isolated left ventricular diastolic dysfunction, left atrial dysfunction, abnormal right ventricular-pulmonary artery coupling, ischemia, or obesity phenotypes. In addition, imaging enables risk stratification for HFpEF. This article provides a critical appraisal of the role of echocardiography in the diagnosis and evaluation of HFpEF.

摘要

在射血分数保留的心力衰竭(HFpEF)的评估中,非侵入性成像,特别是超声心动图,起着核心作用。当诊断不确定时,超声心动图有助于在不明原因呼吸困难的患者中诊断 HFpEF。在已确诊的 HFpEF 中,超声心动图为病理生理学和表型提供了重要的见解,例如孤立的左心室舒张功能障碍、左心房功能障碍、异常的右心室-肺动脉耦联、缺血或肥胖表型。此外,成像能够对 HFpEF 进行风险分层。本文批判性地评价了超声心动图在 HFpEF 的诊断和评估中的作用。

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Eur Heart J. 2018 Oct 1;39(37):3439-3450. doi: 10.1093/eurheartj/ehy531.
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Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.特发性甲状腺素运载蛋白淀粉样变心肌病患者的塔法米迪治疗。
N Engl J Med. 2018 Sep 13;379(11):1007-1016. doi: 10.1056/NEJMoa1805689. Epub 2018 Aug 27.
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Myocardial Injury and Cardiac Reserve in Patients With Heart Failure and Preserved Ejection Fraction.
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