Yang Shuhui, Zhang Zhanmei, Liu Yulin, Liu Enmei, Luo Zhengxiu
Department of Respiratory Disease, Children's Hospital of Chongqing Medical University/ National Clinical Research Center for Child Health and Disorders/ Ministry of Education Key Laboratory of Child Development and Disorders/ Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.
J Asthma Allergy. 2023 Mar 15;16:293-303. doi: 10.2147/JAA.S398108. eCollection 2023.
To investigate the effects of combined respiratory muscle and exercise training on inspiratory muscle strength, exercise capacity, spirometry measurements, asthma control the quality-of-life in children with asthma.
Fifty children with asthma, who were treated in children's hospital of Chongqing medical university in Chongqing between May and December 2021, were selected and randomly divided into a rehabilitation group and a control group by using a random number table. The control group was given routine drug treatment and health education while the rehabilitation group received a combination of respiratory muscle and exercise training on the basis of control group.
After three months of treatment, the maximum inspiratory pressure, level of asthma control and quality-of-life in the rehabilitation group were significantly improved when compared with those in the control group (P<0.05); there were no significant differences in the 6-minute walking test and spirometry measurements (P>0.05). After three months of treatment, all outcome indicators in the rehabilitation group were significantly improved when compared to those before treatment (P<0.05). The mean value of maximum inspiratory pressure and some indices of spirometry measurements in the control group were significantly improved when compared to those before treatment (P<0.05).
Combining respiratory muscle and exercise training on the basis of the routine drug treatment and health education significantly improved inspiratory muscle strength, the level of asthma control and the quality-of-life in children with asthma. More research is needed to explore its role in asthma in the future.
探讨呼吸肌与运动训练相结合对哮喘儿童吸气肌力量、运动能力、肺功能测量、哮喘控制及生活质量的影响。
选取2021年5月至12月在重庆医科大学附属儿童医院接受治疗的50例哮喘儿童，采用随机数字表法将其随机分为康复组和对照组。对照组给予常规药物治疗和健康教育，康复组在对照组基础上接受呼吸肌与运动训练相结合的治疗。
治疗3个月后，康复组的最大吸气压、哮喘控制水平及生活质量较对照组显著改善（P<0.05）；6分钟步行试验和肺功能测量结果差异无统计学意义（P>0.05）。治疗3个月后，康复组各项观察指标较治疗前均显著改善（P<0.05）。对照组最大吸气压均值及部分肺功能测量指标较治疗前显著改善（P<0.05）。
在常规药物治疗和健康教育基础上，结合呼吸肌与运动训练可显著提高哮喘儿童的吸气肌力量、哮喘控制水平及生活质量。未来还需要更多研究来探索其在哮喘中的作用。
