Schaller Nina, Blume Katharina, Hornig Markus, Senker Ludger, Wolfarth Bernd, Schuster Tibor, Halle Martin, Esefeld Katrin
Department of Prevention, Rehabilitation and Sports Medicine, University Hospital (Klinikum rechts der Isar), Technical University of Munich, Georg-Brauchle-Ring 56, 80992, Munich, Germany.
Department of Sports Medicine, Humboldt-University, Charité University Medicine, Berlin, Germany.
J Occup Med Toxicol. 2023 Mar 22;18(1):4. doi: 10.1186/s12995-023-00370-w.
Occupational health programmes have been successfully implemented to improve body composition, physical fitness and cardiovascular risk. However, most programmes have been small and have not included long-term evaluation. Therefore, we evaluated a twelve-month life-style change programme in a German refinery.
We offered a supervised six-week endurance exercise programme (2 × 90 min/week), starting after a two-day life-style seminar. After the active intervention and a half-day refresher seminar, employees were encouraged to continue exercising over one year on their own, with monthly supervised sessions to maintain adherence. Anthropometry, bicycle ergometry, cardio-metabolic risk profile, inflammatory parameters, and vascular function e.g. endothelial function was studied at baseline, after three and after twelve months.
Of 550 employees, n = 327 (age 40.8 ± 9.7 years, 88% males) participated in the study. Twelve-month intervention was associated with a reduced waist circumference (92.6 ± 12.2 to 90.8 ± 11.7 cm, 95% confidence interval for the mean change (CI): -2.5 to -1.1 cm) and a gain in maximal exercise capacity (202 ± 39.6 to 210 ± 38.9 Watt; 95% CI: + 5.1 to + 10.9 Watt). Metabolic and inflammatory parameters likewise HbA and C-reactive protein improved in central tendency at a local 95% level of confidence. Vascular function e.g. Reactive-Hyperaemia-Index revealed a slight reduction, whereas no statistically robust changes in mean Cardio-Ankle-Vascular-Index and mean Ankle-Brachial-Index were observed.
Health education added by a six-week supervised exercise programme was associated with minor long-term twelve-month improvements of body composition as well as physical fitness and a concomitant improvement of inflammatory state. These changes were, however, not clinically relevant and not accompanied by statistically robust improvements of vascular function.
ClinTrialsGov: NCT01919632; date of registration: August 9, 2013; retrospectively registered.
职业健康计划已成功实施，以改善身体成分、身体素质和心血管疾病风险。然而，大多数计划规模较小，且未包括长期评估。因此，我们在一家德国炼油厂评估了一项为期十二个月的生活方式改变计划。
我们提供了一项为期六周的有监督耐力运动计划（每周2次，每次90分钟），在为期两天的生活方式研讨会后开始。在积极干预和半天的复习研讨会之后，鼓励员工自行继续锻炼一年，每月有监督课程以维持依从性。在基线、三个月后和十二个月后研究人体测量学、自行车测力计测试、心脏代谢风险概况、炎症参数和血管功能，如内皮功能。
550名员工中，n = 327人（年龄40.8±9.7岁，88%为男性）参与了研究。十二个月的干预与腰围减小（从92.6±12.2厘米降至90.8±11.7厘米，平均变化的95%置信区间（CI）：-2.5至-1.1厘米）以及最大运动能力增加（从202±39.6瓦增至210±38.9瓦；95%CI：+5.1至+10.9瓦）相关。代谢和炎症参数同样，糖化血红蛋白（HbA）和C反应蛋白在局部95%置信水平上呈中心趋势改善。血管功能，如反应性充血指数略有降低，而心脏-脚踝血管指数和脚踝-臂指数的平均值未观察到统计学上显著的变化。
为期六周的有监督运动计划附加健康教育与身体成分、身体素质在十二个月的长期轻微改善以及炎症状态的相应改善相关。然而，这些变化在临床上并不相关，也没有伴随着血管功能在统计学上的显著改善。
ClinicalTrialsGov：NCT01919632；注册日期：2013年8月9日；回顾性注册。
