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进化生物心理社会医学

Evobiopsychosocial medicine.

作者信息

Hunt Adam D, St-John Smith Paul, Abed Riadh

机构信息

Institute for Evolutionary Medicine, University of Zürich, Zürich, Switzerland.

Evolutionary Psychiatry Special Interest Group, Royal College of Psychiatrists, London, UK.

出版信息

Evol Med Public Health. 2022 Nov 22;11(1):67-77. doi: 10.1093/emph/eoac041. eCollection 2023.

DOI:10.1093/emph/eoac041
PMID:36950197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10026618/
Abstract

The biopsychosocial model remains the de facto framework of current healthcare, but lacks causational depth, scientific rigour, or any recognition of the importance of evolutionary theory for understanding health and disease. In this article it is updated to integrate Tinbergen's four questions with the three biopsychosocial levels. This 'evobiopsychosocial' schema provides a more complete framework for understanding causation of medical conditions. Its application is exemplified by tabulating depression, rheumatoid arthritis and COVID-19 within its format, which highlights the direct research and practical applications uniquely offered by evolutionary medicine. An evobiopsychosocial framework can serve as a useful tool to introduce evolutionary concepts into mainstream medicine by highlighting the broad and specific contributions of evolutionary analysis to researching, treating and preventing health conditions, providing a suitable next step for the mainstream model of medicine.

摘要

生物心理社会模型仍然是当前医疗保健的实际框架,但缺乏因果深度、科学严谨性,也未认识到进化理论对理解健康与疾病的重要性。在本文中,它被更新以将廷伯根的四个问题与生物心理社会的三个层次相结合。这种“进化生物心理社会”模式为理解医疗状况的病因提供了一个更完整的框架。通过在其框架内将抑郁症、类风湿性关节炎和新冠肺炎制成表格来说明其应用,这突出了进化医学独特提供的直接研究和实际应用。一个进化生物心理社会框架可以作为一个有用的工具,通过强调进化分析对研究、治疗和预防健康状况的广泛和具体贡献,将进化概念引入主流医学,为医学的主流模式提供合适的下一步发展方向。

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BJPsych Bull. 2023 Aug;47(4):224-228. doi: 10.1192/bjb.2022.36.
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Rapid evolution of SARS-CoV-2 challenges human defenses.SARS-CoV-2 的快速进化挑战了人类的防御能力。
Sci Rep. 2022 Apr 19;12(1):6457. doi: 10.1038/s41598-022-10097-z.
3
Why Do People (Not) Engage in Social Distancing? Proximate and Ultimate Analyses of Norm-Following During the COVID-19 Pandemic.为什么人们(不)遵守社交距离规定?对新冠疫情期间规范遵循行为的近因和终极分析。
Front Psychol. 2021 Jun 23;12:648206. doi: 10.3389/fpsyg.2021.648206. eCollection 2021.
4
The influence of evolutionary history on human health and disease.进化史对人类健康和疾病的影响。
Nat Rev Genet. 2021 May;22(5):269-283. doi: 10.1038/s41576-020-00305-9. Epub 2021 Jan 6.
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Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom.爱尔兰和英国与新冠疫苗犹豫及抵触相关的心理特征。
Nat Commun. 2021 Jan 4;12(1):29. doi: 10.1038/s41467-020-20226-9.
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Risk factors for severe and critically ill COVID-19 patients: A review.COVID-19 患者重症和危重症的危险因素:综述。
Allergy. 2021 Feb;76(2):428-455. doi: 10.1111/all.14657. Epub 2020 Dec 4.
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Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19).关于 19 冠状病毒病(COVID-19)的遗传学、进化、免疫发病机制和传播的最新知识更新。
Int J Biol Sci. 2020 Sep 12;16(15):2906-2923. doi: 10.7150/ijbs.48812. eCollection 2020.
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Impact of lockdown on Covid-19 case fatality rate and viral mutations spread in 7 countries in Europe and North America.封锁对欧洲和北美 7 个国家的新冠病毒病死率和病毒突变传播的影响。
J Transl Med. 2020 Sep 2;18(1):338. doi: 10.1186/s12967-020-02501-x.
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Nat Rev Clin Oncol. 2020 Nov;17(11):675-686. doi: 10.1038/s41571-020-0411-1. Epub 2020 Jul 22.
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