Mohamad Haron Didi Erwandi, Yoneda Minoru, Ahmad Emmy Dayana, Aziz Mohd Yusmaidie
Department of Environmental Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan.
Centre of Research Service, Institute of Research Management and Services, Deputy Vice-Chancellor (Research and Renovation), Universiti Malaya, Kuala Lumpur, Malaysia.
Food Addit Contam Part B Surveill. 2023 Jun;16(2):161-175. doi: 10.1080/19393210.2023.2188611. Epub 2023 Mar 23.
Endocrine disrupting chemicals (EDCs) such as per- and polyfluoroalkyl substances (PFAS), bisphenols, and parabens are used in food packaging or as preservatives and their unintended consumption has been associated with cancer and other diseases. Food EDCs data are scarce in Malaysia. Thus, liquid chromatography mass tandem spectrometry (LC-MS/MS) was utilised to analyse 18 EDCs from different food categories. Bisphenol was the most abundant EDC found, followed by PFAS and paraben. Bisphenol levels in canned foods, dairy products, canned drinks, fruits, and vegetables ranged from 1.16 to 183 ng/g. PFAS was found in almost every food category, with canned foods having the highest concentrations (0.18-34.5 ng/g). Only canned foods, fruits, and vegetables contained parabens, with mean concentrations ranging from 0.27 to 26.7 ng/g. PFOS, PFBA, PFHQA and bisphenol A all had hazard quotients (HQ) above 1, indicating that they can pose a risk to human health.
全氟和多氟烷基物质（PFAS）、双酚和对羟基苯甲酸酯等内分泌干扰化学物质（EDC）被用于食品包装或作为防腐剂，意外摄入这些物质与癌症及其他疾病有关。马来西亚的食品中EDC数据匮乏。因此，采用液相色谱串联质谱法（LC-MS/MS）分析了不同食品类别中的18种EDC。发现双酚是含量最高的EDC，其次是PFAS和对羟基苯甲酸酯。罐装食品、乳制品、罐装饮料、水果和蔬菜中的双酚含量在1.16至183纳克/克之间。几乎在每个食品类别中都发现了PFAS，其中罐装食品中的浓度最高（0.18 - 34.5纳克/克）。只有罐装食品、水果和蔬菜中含有对羟基苯甲酸酯，平均浓度在0.27至26.7纳克/克之间。全氟辛烷磺酸（PFOS）、全氟丁酸（PFBA）、全氟己基磺酸（PFHQA）和双酚A的危害商数（HQ）均高于1，表明它们可能对人体健康构成风险。
