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心脏手术后发生术后黄疸一例。

A Case of Post-operative Jaundice After Cardiac Surgery.

作者信息

Alabi Fortune O, Alabi Christopher O, Waldon Brent, Umeh Fred C, Palmer George

机构信息

Pulmonary Medicine, Critical Care and Sleep Medicine, Florida Lung, Asthma & Sleep Specialists, Orlando, USA.

Internal Medicine, HCA East Florida Westside Hospital/Northwest Hospital, Plantation, USA.

出版信息

Cureus. 2023 Feb 19;15(2):e35190. doi: 10.7759/cureus.35190. eCollection 2023 Feb.

DOI:10.7759/cureus.35190
PMID:36960260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10030160/
Abstract

Hyperbilirubinemia is a common gastrointestinal complication seen post-cardiac surgery. Here, we describe a case of a 72-year-old male with a past medical history of chronic obstructive pulmonary disease, chronic kidney disease (CKD), pulmonary hypertension, and valvular heart disease with severe aortic stenosis, severe mitral and tricuspid regurgitations who underwent elective aortic valve replacement (AVR), mitral valve replacement (MVR), and tricuspid valve (TV) repair; in addition, he required left thoracotomy for the repair of pulmonary artery perforation from a Swan-Ganz catheter that resulted in a large left pleural bleed. Post-operatively, he developed severe jaundice, which was predominantly conjugated that peaked at 24 mg/dL. He also required multiple blood products' transfusion in the perioperative period and was supported temporarily with hemodialysis for acute kidney injury superimposed on his CKD. He underwent extensive evaluation for jaundice, which included ultrasound of the liver, hepatobiliary iminodiacetic (HIDA) scan, and magnetic resonance cholangiopancreatography (MRCP), which were all normal. The patient eventually got better and was discharged from the hospital. The hyperbilirubinemia slowly got better without any specific therapy and on his follow-up visit to the office following discharge, his bilirubin level was found completely normalized. Although most cases of post-cardiac surgery hyperbilirubinemia resolve without any specific therapy, the occurrence is not completely benign since it can increase morbidity and mortality. It is paramount that intensivists and cardiothoracic surgeons caring for these patients are aware of this occurrence to prevent unnecessary diagnostic evaluation. Most early cases of hyperbilirubinemia are transient and do not usually increase morbidity and mortality. In the late cases, infectious etiology resulting in sepsis needs to be entertained early and treated aggressively.

摘要

高胆红素血症是心脏手术后常见的胃肠道并发症。在此,我们描述一例72岁男性患者,他有慢性阻塞性肺疾病、慢性肾脏病(CKD)、肺动脉高压和瓣膜性心脏病病史,伴有严重主动脉瓣狭窄、严重二尖瓣和三尖瓣反流,接受了择期主动脉瓣置换术(AVR)、二尖瓣置换术(MVR)和三尖瓣(TV)修复;此外,他因Swan - Ganz导管导致肺动脉穿孔并引起大量左侧胸腔出血而需要左胸切开术进行修复。术后,他出现了严重黄疸,主要为结合胆红素升高,峰值达24mg/dL。他在围手术期还需要多次输血,并因CKD基础上叠加的急性肾损伤而接受了短期血液透析支持。他接受了针对黄疸的广泛评估,包括肝脏超声、肝胆亚氨基二乙酸(HIDA)扫描和磁共振胰胆管造影(MRCP),结果均正常。患者最终病情好转并出院。高胆红素血症在未进行任何特殊治疗的情况下逐渐好转,出院后随访时发现其胆红素水平已完全恢复正常。虽然大多数心脏手术后高胆红素血症病例无需特殊治疗即可缓解,但其发生并非完全无害,因为它可能增加发病率和死亡率。至关重要的是,照顾这些患者的重症监护医生和心胸外科医生应意识到这种情况的发生,以避免不必要的诊断评估。大多数早期高胆红素血症病例是短暂的,通常不会增加发病率和死亡率。在晚期病例中,需要尽早考虑感染性病因导致的败血症并积极治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cac3/10030160/328093eb0e4e/cureus-0015-00000035190-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cac3/10030160/328093eb0e4e/cureus-0015-00000035190-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cac3/10030160/328093eb0e4e/cureus-0015-00000035190-i01.jpg

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Hyperbilirubinemia after cardiac surgery: An observational study.心脏手术后的高胆红素血症:一项观察性研究。
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