Hoover Christopher M, Skaff Nicholas K, Blumberg Seth, Fukunaga Rena
Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
PLOS Glob Public Health. 2023 Jan 6;3(1):e0001302. doi: 10.1371/journal.pgph.0001302. eCollection 2023.
COVID-19 outbreaks in congregate settings remain a serious threat to the health of disproportionately affected populations such as people experiencing incarceration or homelessness, the elderly, and essential workers. An individual-based model accounting for individual infectiousness over time, staff work schedules, and testing and isolation schedules was developed to simulate community transmission of SARS-CoV-2 to staff in a congregate facility and subsequent transmission within the facility that could cause an outbreak. Systematic testing strategies in which staff are tested on the first day of their workweek were found to prevent up to 16% more infections than testing strategies unrelated to staff schedules. Testing staff at the beginning of their workweek, implementing timely isolation following testing, limiting test turnaround time, and increasing test frequency in high transmission scenarios can supplement additional mitigation measures to aid outbreak prevention in congregate settings.
集体环境中的新冠疫情对受影响尤为严重的人群的健康仍然构成严重威胁,这些人群包括被监禁者、无家可归者、老年人和一线工作者。我们开发了一个基于个体的模型,该模型考虑了个体随时间的传染性、工作人员的工作时间表以及检测和隔离时间表,以模拟严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在集体设施中向工作人员的社区传播,以及随后在设施内可能导致疫情爆发的传播情况。研究发现,与工作人员时间表无关的检测策略相比,在工作人员工作周的第一天进行检测的系统检测策略可多预防高达16%的感染。在工作人员工作周开始时对其进行检测、检测后及时进行隔离、缩短检测周转时间以及在高传播情况下增加检测频率,可以补充其他缓解措施,以帮助预防集体环境中的疫情爆发。