University of Yamanashi Faculty of Medicine Graduate School of Medicine, Chuo City, Japan.
The University of Tokyo Institute of Medical Science, Minato-ku, Japan.
Stem Cell Reports. 2023 Apr 11;18(4):799-806. doi: 10.1016/j.stemcr.2023.02.005. Epub 2023 Mar 23.
The International Society for Stem Cell Research (ISSCR) has eliminated its prohibition on research involving the culturing of human embryos beyond 14 days within the updated 2021 guidelines. We conducted a survey of Japanese researchers working in stem cell- or embryo-related research (n = 535) and the public (n = 3,000) about their attitudes toward the 14-day rule. Among the researchers, 46.2% agreed that embryos could be cultured beyond 14 days, a result that was slightly lower among the public (37.9%). Among those that disagreed with embryo culturing beyond 14 days, 9.5% of researchers and 5.1% of the public agreed with culturing embryos within 14 days. Among the public, higher comprehension levels correlated with both agreement and disagreement with the culture of embryos beyond 14 days compared with "cannot judge." Further research and pubic discourse are necessary in order to better understand the factors informing participant decisions regarding the 14-day rule.
国际干细胞研究学会（ISSCR）在其更新的 2021 年指南中取消了禁止培养超过 14 天的人类胚胎的规定。我们对从事干细胞或胚胎相关研究的日本研究人员（n=535）和公众（n=3000）进行了一项关于他们对 14 天规则的态度的调查。在研究人员中，46.2%的人同意可以培养超过 14 天的胚胎，而公众中的这一比例略低（37.9%）。在不同意培养超过 14 天的胚胎的人中，9.5%的研究人员和 5.1%的公众同意在 14 天内培养胚胎。在公众中，与“无法判断”相比，较高的理解水平与同意和不同意培养超过 14 天的胚胎呈正相关。为了更好地了解参与者对 14 天规则的决策所依据的因素，需要进一步研究和公众讨论。
