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关注老年人的感染问题。

Focusing on infection in the elderly.

机构信息

Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu, China.

出版信息

Front Cell Infect Microbiol. 2023 Mar 10;13:1121947. doi: 10.3389/fcimb.2023.1121947. eCollection 2023.

Abstract

As a confirmed carcinogen, Helicobacter pylori () is the main cause of inflammatory diseases of the upper digestive tract and even gastric cancer. There is a high prevalence of infection among the elderly population, which may cause adverse clinical outcomes. Particularly noteworthy is that guidelines or expert consensus presently available on infection overlook the management of the elderly population as a special group. A brief overview of in the elderly is as follows. The detection of infection can be divided into invasive and non-invasive techniques, and each technique has its advantages and shortcomings. There may be more side effects associated with eradication treatment in elderly individuals, especially for the frail population. Physical conditions and risk-benefit assessments of the elderly should be considered when selecting therapeutic strategies for eradication. Unless there are competing factors, elderly patients should receive eradication regimens to finally reduce the formation of gastric cancer. In this review, we summarize the latest understanding of in the elderly population to provide effective managements and treatment measures.

摘要

幽门螺杆菌()作为一种确认的致癌物质,是引起上消化道炎症性疾病甚至胃癌的主要原因。老年人中存在较高的感染率,这可能导致不良的临床结局。值得特别注意的是,目前关于感染的指南或专家共识忽略了老年人这一特殊群体的管理。老年人感染的简要概述如下。感染的检测可分为有创和非侵入性技术,每种技术都有其优点和缺点。根除治疗在老年人中可能会出现更多的副作用,尤其是在体弱人群中。在选择根除治疗策略时,应考虑老年人的身体状况和风险效益评估。除非存在竞争因素,否则老年患者应接受根除治疗方案,以最终减少胃癌的形成。在这篇综述中,我们总结了关于老年人感染的最新认识,以提供有效的管理和治疗措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3828/10036784/a2a2b0406045/fcimb-13-1121947-g001.jpg

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