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原发性胰腺未分化多形性肉瘤

Primary Pancreatic Undifferentiated Pleomorphic Sarcoma.

作者信息

Patel Mehrie Harshad, Guerrero Vinsard Daniela, Agrawal Upasana, Kendziora Ryan W, Siontis Brittany L, Swaroop Vege Santhi, Sweetser Seth

机构信息

Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.

Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

出版信息

ACG Case Rep J. 2023 Mar 22;10(3):e01011. doi: 10.14309/crj.0000000000001011. eCollection 2023 Mar.

DOI:10.14309/crj.0000000000001011
PMID:36968124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10036072/
Abstract

Primary pancreatic sarcomas are rare malignancies with an incidence of 0.1%. This case report is of a 48-year-old man who presented with this condition. The patient's treatment plan consisted of distal pancreatectomy and splenectomy with intraoperative immunohistochemistry and adjuvant chemotherapy. To correctly identify and treat undifferentiated pleomorphic sarcoma, a stepwise strategy involving cross-sectional imaging and extensive histopathology analysis is necessary.

摘要

原发性胰腺肉瘤是罕见的恶性肿瘤，发病率为0.1%。本病例报告的是一名患有此病的48岁男性。患者的治疗方案包括胰体尾切除术和脾切除术，并进行术中免疫组化及辅助化疗。为了正确识别和治疗未分化多形性肉瘤，需要采取包括横断面成像和广泛组织病理学分析的分步策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/303fd2b0757c/ac9-10-e01011-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/37e7a58c44ce/ac9-10-e01011-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/233bd9a487f5/ac9-10-e01011-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/cea3d3f7aa83/ac9-10-e01011-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/303fd2b0757c/ac9-10-e01011-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/37e7a58c44ce/ac9-10-e01011-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/233bd9a487f5/ac9-10-e01011-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/cea3d3f7aa83/ac9-10-e01011-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b761/10036072/303fd2b0757c/ac9-10-e01011-g004.jpg

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本文引用的文献

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Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.软组织肉瘤，第 2.2022 版，NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2022 Jul;20(7):815-833. doi: 10.6004/jnccn.2022.0035.
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Undifferentiated pleomorphic sarcoma of the pancreas: a rare case report and literature review.胰腺未分化多形性肉瘤：一例罕见病例报告并文献复习。
World J Surg Oncol. 2022 Feb 27;20(1):55. doi: 10.1186/s12957-022-02525-1.
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The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial.
化疗对肢体和躯干壁软组织肉瘤患者生存的影响：重新审视 EORTC-STBSG 62931 随机试验的结果。
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Undifferentiated Pleomorphic Sarcoma of Pancreas: A Case Report and Review of the Literature for the Last Updates.胰腺未分化多形性肉瘤：一例报告及近期文献综述
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Pain sensation in pancreatic diseases is not uniform: the different facets of pancreatic pain.胰腺疾病中的疼痛感觉并不一致：胰腺疼痛的不同方面。
World J Gastroenterol. 2014 Jul 21;20(27):9154-61. doi: 10.3748/wjg.v20.i27.9154.
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Adjuvant chemotherapy with doxorubicin, ifosfamide, and lenograstim for resected soft-tissue sarcoma (EORTC 62931): a multicentre randomised controlled trial.多柔比星、异环磷酰胺和粒细胞集落刺激因子辅助化疗治疗切除的软组织肉瘤（EORTC 62931）：一项多中心随机对照试验。
Lancet Oncol. 2012 Oct;13(10):1045-54. doi: 10.1016/S1470-2045(12)70346-7. Epub 2012 Sep 4.
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Primary sarcoma of the pancreas, a rare histopathological entity. A case report with review of literature.胰腺原发性肉瘤，一种罕见的组织病理学实体。附文献复习的病例报告。
World J Surg Oncol. 2011 Aug 3;9:85. doi: 10.1186/1477-7819-9-85.
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Primary malignant fibrous histiocytoma of the pancreas: benefit of the multidisciplinary approach.胰腺原发性恶性纤维组织细胞瘤：多学科方法的益处。
Eur J Gastroenterol Hepatol. 2010 Jun;22(6):765-8.
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World J Gastroenterol. 2008 May 14;14(18):2942-5. doi: 10.3748/wjg.14.2942.
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