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泪腺黏液表皮样癌伴对侧眼及全身转移:1例罕见病例报告并文献复习

Lacrimal gland mucoepidermoid carcinoma with contralateral eye and systemic metastasis: A rare case report and review of the literature.

作者信息

Wu Yi, He Weimin

机构信息

Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

出版信息

Front Oncol. 2023 Mar 9;13:1131587. doi: 10.3389/fonc.2023.1131587. eCollection 2023.

Abstract

Lacrimal gland mucoepidermoid carcinoma is very rare. It has a high risk of recurrence and metastasis, however, it rarely metastasizes to the contralateral eye in clinical practice. Here, we present a case of a 52-year-old man with lacrimal gland mucoepidermoid carcinoma who developed multiple recurrences and metastases of another eye and other sites throughout the body after receiving surgical intervention and regular radiotherapy, which will be of ophthalmic interest and unique. Clinical features, imaging findings, histopathology, treatments, and outcomes of this very rare case are provided. A literature review of previously published cases of this disease is performed, with an emphasis on the latest diagnosis and treatment. The prognosis of tumor recurrence and metastasis is poorer, surgery with a negative margin in conjunction with adjuvant therapies is crucial for preventing local recurrence and distant metastasis and enhancing the survival rate.

摘要

泪腺黏液表皮样癌非常罕见。它具有较高的复发和转移风险,然而,在临床实践中它很少转移至对侧眼。在此,我们报告一例52岁男性泪腺黏液表皮样癌患者,其在接受手术干预和常规放疗后,对侧眼及全身其他部位出现多次复发和转移,这将引起眼科领域的关注且具有独特性。本文提供了该罕见病例的临床特征、影像学表现、组织病理学、治疗方法及结果。同时对既往发表的该疾病病例进行了文献综述,重点关注最新的诊断和治疗方法。肿瘤复发和转移的预后较差,切缘阴性的手术联合辅助治疗对于预防局部复发和远处转移以及提高生存率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/990a/10034102/3e4f0d3cc45d/fonc-13-1131587-g001.jpg

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